DIAGNOSIS AND PHARMACOTHERAPY OF PELVIC INFLAMMATORY DISEASES IN WOMEN
DIAGNOSIS AND PHARMACOTHERAPY OF PELVIC INFLAMMATORY DISEASES IN WOMEN
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女性盆腔炎症性疾病的诊断和药物治疗
DOI：
10.18821/2313-8726-2018-5-4-177-181
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
E. Skvortsova
中科院分区：
文献类型：
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作者：
V. Skvortsov;M. Lunkov;E. Skvortsova
本文致力于现代病因学问题，特别是生物膜理论作为最有前途的研究方向。生物膜通常由微生物的关联来表示，它们通过密切接触共存，获得新的特性，表现为非典型的临床表现。这决定了快速诊断和发病机制的问题，其中局部和全身继发性免疫缺陷状态都是最重要的，自身免疫性炎症和自由基氧化反应。盆腔器官炎症性疾病的最典型症状和体征尤其包括慢性输卵管卵巢炎——这是这一群体的常见疾病，具有重要的社会和人口意义，因为根据统计，受影响最严重的群体是育龄妇女。重点放在诊断方法上，不仅使用收集的病史和体格检查数据，还使用基于现代仪器和微创方法的方法。特别重视旨在纠正危险因素和预防这种疾病的措施，提出最合理的抗生素治疗方案的致因治疗，在根除致病微生物或其在生物膜组成中的关联之前缓解病情的病原和对症治疗，以及纠正阴道生态失调等令人不快的并发症。它可以在强力抗生素治疗的背景下发展，而不是治疗不充分和改变所选方案的衡量标准。
The article is devoted to modern issues of etiology, in particular, the theory of biofilms as the most promising direction of research. Biofilms are most often represented by the association of microorganisms in which they, through coexistence in close contacts, acquire new properties, expressed in an atypical clinical picture. This determines problems of rapid diagnosis and pathogenesis, in which both the local and systemic secondary immunodeficiency state is put in the forefront, autoimmune inflammation and reactions of free radical oxidation. The most typical symptoms and signs of inflammatory diseases of the pelvic organs include, in particular, chronic salpingo-oophoritis - a common nosological item from this group, which has important social and demographic significance, since the most affected group, according to statistics, are women of reproductive age. The emphasis was placed on approaches to diagnosis using not only data from the collected history and physical examination but also methods based on modern instrumental and minimally invasive methods. Special attention was paid to measures aimed at correcting risk factors and preventing this disease, etiotropic therapy with the presentation of a specific scheme of the most rational antibiotic therapy, pathogenetic and symptomatic treatment to alleviate the condition before the eradication of the pathogenic microorganism or their association in the composition of biofilms and cure patients, and correction such unpleasant complications as vaginal dysbiosis, which can develop against a background of powerful antibiotic therapy and is not a measure of inadequate treatment and change of the selected regimen.