Bioactive saponins and glycosides.: XXVIII.: New triterpene saponins, foliatheasaponins I, II, III, IV, and V, from Tencha (the leaves of Camellia sinensis)
Bioactive saponins and glycosides.: XXVIII.: New triterpene saponins, foliatheasaponins I, II, III, IV, and V, from Tencha (the leaves of Camellia sinensis)
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DOI：
10.1248/cpb.55.293
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发表时间：
2007-02-01
影响因子：
1.7
通讯作者：
Yoshikawa, Masayuki
中科院分区：
文献类型：
--
作者：
Morikawa, Toshio;Nakamura, Seikou;Yoshikawa, Masayuki
新的三萜皂苷，叶皂苷 I-V，是从 Tencha [Camellia sinensis (L.) O. KUNTZE (Theaceae) 的叶子] 的甲醇提取物中分离出来的。这些新皂苷的化学结构在化学和物理化学证据的基础上得到了阐明。在新的皂苷中，叶皂苷 II 和 III 被发现可以抑制 RBL-2H3 细胞中 β-己糖胺酶的释放，β-己糖胺酶是 RBL-2H3 细胞中抗原诱导脱颗粒的标志物。
New triterpene saponins, foliatheasaponins I-V, were isolated from the methanolic extract of Tencha [the leaves of Camellia sinensis (L.) O. KUNTZE (Theaceae)]. The chemical structures of these new saponins were elucidated on the basis of chemical and physicochernical evidence. Among the new saponins, foliatheasaponins II and III, were found to inhibit release of beta-hexosaminidase, as a marker of antigen-induced degranulation, in RBL-2H3 cells.