Polymer surfaces derivatized with poly(vinyl-N-hexylpyridinium) kill airborne and waterborne bacteria
Polymer surfaces derivatized with poly(vinyl-N-hexylpyridinium) kill airborne and waterborne bacteria
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DOI：
10.1002/bit.10299
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发表时间：
2002-08-20
影响因子：
3.8
通讯作者：
Klibanov, AM
中科院分区：
文献类型：
--
作者：
Tiller, JC;Lee, SB;Klibanov, AM
已经开发出一种简便的方法，用于用设计的抗菌聚阳离子聚（溴化乙烯基吡啶）对常见材料的表面进行共价衍生，其中第一个关键步骤涉及用二氧化硅纳米层进行表面涂覆。以这种方式衍生的各种商业合成聚合物具有杀菌作用，它们可以杀死气溶胶或水悬浮液中沉积的高达 99% 的革兰氏阳性和革兰氏阴性细菌。 (C) 2002 年 Wiley 期刊公司
A facile methodology has been developed for covalently derivatizing the surfaces of common materials with a designed antibacterial polycation, poly(vinyl-pyridinium bromide), wherein the first, key step involves surface coating with a nanolayer of silica. Various commercial synthetic polymers derivatized in this manner become bactericidal-they kill up to 99% of deposited, from either an aerosol or an aqueous suspension, Gram-positive and Gram-negative bacteria on contact. (C) 2002 Wiley Periodicals, Inc.