A voxel-based lesion study on facial emotion recognition after penetrating brain injury
A voxel-based lesion study on facial emotion recognition after penetrating brain injury
复制标题
DOI：
10.1093/scan/nss041
复制
发表时间：
2013-08-01
影响因子：
4.2
通讯作者：
Grafman, Jordan
中科院分区：
文献类型：
--
作者：
Dal Monte, Olga;Krueger, Frank;Grafman, Jordan
解读他人情绪的能力是一项重要的社交技能，但患有创伤性脑损伤 (TBI) 的受试者可能会受到损害。为了确定调节面部情绪识别的大脑区域，我们使用经过充分验证的面部情绪识别任务和基于体素的病变症状图谱 (VLSM) 对大量局灶性穿透性 TBI (pTBI) 患者样本进行了全脑分析。我们的结果显示，患有 pTBI 的个体在识别不愉快情绪方面的表现明显比正常对照组差。 VLSM 映射结果显示，面部情绪识别受损是由于双侧额颞边缘网络受损所致，包括内侧前额叶皮层 (PFC)、前扣带皮层、左侧岛叶和颞区。除了这些共同区域外，双侧前额皮质和前额叶区的损伤导致识别不愉快情绪的能力受损，而双侧后额叶皮层和左颞区的损伤导致识别愉快情绪的能力受损。我们的研究结果增加了经验证据，表明读取他人脸上愉快和不愉快情绪的能力是一个复杂的过程，不仅涉及包括双边额颞叶边缘叶的共同网络，还涉及取决于情绪效价的其他区域。
The ability to read emotions in the face of another person is an important social skill that can be impaired in subjects with traumatic brain injury (TBI). To determine the brain regions that modulate facial emotion recognition, we conducted a whole-brain analysis using a well-validated facial emotion recognition task and voxel-based lesion symptom mapping (VLSM) in a large sample of patients with focal penetrating TBIs (pTBIs). Our results revealed that individuals with pTBI performed significantly worse than normal controls in recognizing unpleasant emotions. VLSM mapping results showed that impairment in facial emotion recognition was due to damage in a bilateral fronto-temporo-limbic network, including medial prefrontal cortex (PFC), anterior cingulate cortex, left insula and temporal areas. Beside those common areas, damage to the bilateral and anterior regions of PFC led to impairment in recognizing unpleasant emotions, whereas bilateral posterior PFC and left temporal areas led to impairment in recognizing pleasant emotions. Our findings add empirical evidence that the ability to read pleasant and unpleasant emotions in other people's faces is a complex process involving not only a common network that includes bilateral fronto-temporo-limbic lobes, but also other regions depending on emotional valence.