Obesity, obstetric complications and cesarean delivery rate - A population-based screening study

Obesity, obstetric complications and cesarean delivery rate - A population-based screening study
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DOI:
10.1016/j.ajog.2003.09.058
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发表时间:
2004-04-01
影响因子:
9.8
通讯作者:
D'Alton, ME
D'Alton, ME
中科院分区:
医学1区
文献类型:
--
作者:
Weiss, JL;Malone, FD;D'Alton, ME

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目的:本研究旨在确定肥胖是否与产科并发症和剖宫产有关。方法:对一个大型前瞻性多中心数据库进行研究。受试者分为3组:体重指数(BMI)小于30(对照组),30至34.9(肥胖),35或更大(病态肥胖)。通过单变量和多变量logistic回归分析比较各组。结果:该研究包括16,102例患者:3,752例对照,1,473例肥胖和877例病态肥胖患者。肥胖和病态肥胖与妊娠期高血压(比值比[OR] 2.5和3.2)、先兆子痫(OR 1.6和3.3)、妊娠期糖尿病(OR 2.6和4.0)和胎儿出生体重大于4000 g(OR 1.7和1.9)和大于4500 g(OR 2.0和2.4)具有统计学显著相关性。对于未经产的患者,剖宫产率为20.7%的对照组,33.8%的肥胖,和47.4%的病态肥胖patients.Conclusion:肥胖是一个独立的危险因素,不良产科结局,并显着增加剖宫产率。(C)2004爱思唯尔公司All rights reserved.
Objective: This study was undertaken to determine whether obesity is associated with obstetric complications and cesarean delivery.Methods: A large prospective multicenter database was studied. Subjects were divided into 3 groups: body mass index (BMI) less than 30 (control), 30 to 34.9 (obese), and 35 or greater (morbidly obese). Groups were compared by using univariate and multivariable logistic regression analyses.Results: The study included 16,102 patients: 3,752 control, 1,473 obese, and 877 morbidly obese patients. Obesity and morbid obesity had a statistically significant association with gestational hypertension (odds ratios [ORs] 2.5 and 3.2), preeclampsia (ORs 1.6 and 3.3), gestational diabetes (ORs 2.6 and 4.0), and fetal birth weight greater than 4000 g (ORs 1.7 and 1.9) and greater than 4500 g (ORs 2.0 and 2.4). For nulliparous patients, the cesarean delivery rate was 20.7% for the control group, 33.8% for obese, and 47.4% for morbidly obese patients.Conclusion: Obesity is an independent risk factor for adverse obstetric outcome and is significantly associated with an increased cesarean delivery rate. (C) 2004 Elsevier Inc. All rights reserved.