Ectopic gastric mucosa in the cervical esophagus.
Ectopic gastric mucosa in the cervical esophagus.
复制标题
颈段食管的异位胃粘膜。
DOI：
10.1053/ajot.2002.123437
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发表时间：
2002
影响因子：
2.5
通讯作者：
N. Busaba
中科院分区：
文献类型：
--
作者：
Edwin Ishoo;N. Busaba
本研究描述了颈段食管异位胃粘膜（EGM）的临床表现和治疗。这是一名 53 岁男性的病例报告，他出现持续 3 个月的左侧吞咽痛。办公室检查，包括柔性纤维喉镜检查，没有发现任何异常。直接喉镜检查和硬性食管镜检查显示颈部食管内有 2 x 1 厘米的肉质、红色和凸起病变。食管的其余部分正常。病变活检标本的组织学检查显示胃上皮正常，与异位胃粘膜的诊断一致。他接受了 3 个月的质子泵抑制剂治疗，症状完全缓解。随后患者改用 H2 阻滞剂，一年内没有任何症状。回顾了有关颈部食管 EGM 的发病率、发病机制、临床过程和治疗的医学文献。总之，EGM可发生于颈部食管，吞咽痛是其典型症状。在颈部食管的随机、非综合征性 EGM 中发生的腺癌极为罕见。主要的治疗方式是药物治疗。
This study describes the clinical presentation and management of ectopic gastric mucosa (EGM) in the cervical esophagus. This is a case report of a 53-year-old male who presented with left-sided odynophagia of 3 months' duration. Office examination, including flexible fiberoptic laryngoscopy, was unremarkable. Direct larynogoscopy and rigid esophagoscopy revealed a 2 x 1-cm fleshy, red, and raised lesion in the cervical esophagus. The remainder of the esophagus was normal. Histologic examination of a biopsy specimen from the lesion showed a normal gastric epithelium consistent with the diagnosis of ectopic gastric mucosa. He was treated with 3 months of proton pump inhibitors, which resulted in complete symptom resolution. Patient was then switched to H2-blockers and has been symptom-free for one year. The medical literature regarding EGM in the cervical esophagus is reviewed with respect to its incidence, pathogenesis, clinical course, and management. In conclusion, EGM can occur in the cervical esophagus, and odynophagia is the typical presenting symptom. Adenocarcinoma developing within random, nonsyndromic EGM of the cervical esophagus is exceedingly rare. The primary mode of treatment is medical therapy.