The association between sleep-disordered breathing and aortic stiffness in a community cohort
The association between sleep-disordered breathing and aortic stiffness in a community cohort
复制标题
DOI：
10.1016/j.sleep.2015.11.009
复制
发表时间：
2016-03-01
期刊：
影响因子：
4.8
通讯作者：
Gottlieb, Daniel J.
中科院分区：
文献类型：
--
作者：
Chami, Hassan A.;Vasan, Ramachandran S.;Gottlieb, Daniel J.
目的：睡眠呼吸障碍与高血压和心血管疾病有关。主动脉僵硬增加是一种可能的连接机制。我们在一项基于社区的样本中评估了睡眠障碍呼吸和主动脉僵硬之间的关系。方法：我们基于社区的横断面观察性研究包括来自Framingham心脏研究的381名参与者(55%的女性，平均年龄58.0S.D.=9.4岁，51%的少数民族)。多导睡眠图获得的呼吸暂停低通气指数和CT90%(氧合血红蛋白饱和的累计睡眠时间百分比
Objective: Sleep-disordered breathing is associated with hypertension and cardiovascular disease. Increased aortic stiffness is one possible linking mechanism. We evaluated the association between sleep-disordered breathing and aortic stiffness in a community-based sample.Methods: Our community-based cross-sectional observational study included 381 participants from the Framingham Heart Study (55% women, mean age 58.0 S.D. = 9.4 years, 51% ethnic minorities). Polysomnographically derived apnea-hypopnea index and CT90% (cumulative % sleep time with oxyhemoglobin saturation