IN-VITRO EVALUATION OF VENA-CAVA FILTERS
IN-VITRO EVALUATION OF VENA-CAVA FILTERS
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DOI：
10.1016/s1051-0443(94)71627-4
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发表时间：
1994-11-01
影响因子：
2.9
通讯作者：
BARTHELEMY, RP
中科院分区：
文献类型：
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作者：
HAMMER, FD;ROUSSEAU, HP;BARTHELEMY, RP
目的：作者在体外测试了9种腔静脉过滤器，以评估不同实验条件下的凝块捕获能力和跨过滤器压力梯度。材料与方法：采用改进的流动模型对不锈钢格林菲尔德过滤器的过滤效率进行了评价。总共注射了2100个血块。此外，通过使用小型（3 × 30 mm）和中型（5 × 30 mm）凝块，选择模拟体内条件的受控参数，以评估9个过滤器在水平和垂直位置的凝块捕获能力和压力梯度。对3600例凝块分娩进行了统计评估。结果：根据实验条件的不同，格林菲尔德过滤器在使用小块和中型块时的捕凝能力差异很大（0% ~ 78%）。鸟巢和西蒙镍钛诺过滤器对小血块的过滤效率最高（94%-100%）。Bird's Nest、Simon nitinol、Antheor和Gunther Tulip滤镜有效捕获中度凝块（79%-100%）。结论：实验参数影响滤器的凝块捕获能力，鸟巢滤器的凝块捕获能力最高。
PURPOSE: The authors tested in vitro nine caval filters to evaluate clot-trapping capacity and transfilter pressure gradients under varying experimental conditions.MATERIAL AND METHODS: The filtering efficiency of the stainless-steel Greenfield filter was evaluated in a modified flow model. A total of 2,100 clots were injected. In addition, controlled parameters simulating in vivo conditions were selected to appreciate clot-trapping capacity and pressure gradients for nine filters in horizontal and vertical positions, by using small (3 x 30 mm) and medium-sized (5 x 30 mm) clots. Statistical evaluation was performed for 3,600 clot deliveries.RESULTS: Depending on experimental conditions, the clot-trapping capacity of the Greenfield filter varied greatly (0%-78%) by using small and medium clots. Bird's Nest and Simon nitinol filters demonstrated the highest filtering efficiency (94%-100%) for small clots. Medium clots were effectively captured by Bird's Nest, Simon nitinol, Antheor, and Gunther Tulip filters (79%-100%).CONCLUSION: Experimental parameters influence a filter's clot-trapping capacity, Bird's Nest filters demonstrated the highest clot-trapping capacity.