Effect of human immunodeficiency virus type 1 infection upon acute salpingitis: A laparoscopic study

Effect of human immunodeficiency virus type 1 infection upon acute salpingitis: A laparoscopic study
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DOI:
10.1086/314465
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发表时间:
1998-11-01
影响因子:
6.4
通讯作者:
Kreiss, J
Kreiss, J
中科院分区:
医学2区
文献类型:
--
作者:
Cohen, CR;Sinei, S;Kreiss, J

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为了确定人类免疫缺陷病毒1型(HIV-1)感染对盆腔炎(PID)的影响,在肯尼亚内罗毕进行了一项急性PID的腹腔镜研究。受试者接受了诊断性腹腔镜检查、HIV-1血清学检查和性传播疾病检测。输卵管卵巢囊肿(TOA)在33%的HIV-1感染和15%的HIV-1未感染的妇女中被发现(比值比[OR],2.8; 95%置信区间[CI],1.2-6.5)。在血清学阳性的妇女中,55%的CD 4细胞百分比为14%(OR 3.1,95%CI 0.6-15.3)的妇女发现TOA。在37名妇女(28%)中检测到淋病奈瑟菌,在12名妇女(9%)中检测到沙眼衣原体;两者均与HIV-1血清阳性无显著相关性,住院时间总体上不受HIV-1血清状态的影响,但在HIV-1感染的妇女中,CD 4细胞百分比
To determine the effect of human immunodeficiency virus type 1 (HIV-1) infection upon pelvic inflammatory disease (PID), a laparoscopic study of acute PID was conducted in Nairobi, Kenya, Subjects underwent diagnostic laparoscopy, HIV-I serology, and testing for sexually transmitted diseases, Of the 133 women with laparoscopically verified salpingitis, 52 (39%) were HIV-l-seropositive. Tube-ovarian abscesses (TOA) were found in 33% of HIV-1-infected and 15% of HIV-1-uninfected women (odds ratio [OR], 2.8; 95% confidence interval [CI], 1.2-6.5). Among seropositive women, TOA was found in 55% of those with CD4 cell percent 14% (OR 3.1, 95% CI 0.6-15.3). Neisseria gonorrhoeae was detected in 37 women (28%) and Chlamydia trachomatis in 12 (9%); neither was significantly related to HIV-1 seropositivity, Length of hospitalization was not affected by HIV-1 serostatus overall but was prolonged among HIV-l-infected women with CD4 cell percent