Tape-cast and sintered beta-tricalcium phosphate laminates for biomedical applications: Effect of milled A1203 fiber additives on microstructural and
Tape-cast and sintered beta-tricalcium phosphate laminates for biomedical applications: Effect of milled A1203 fiber additives on microstructural and
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用于生物医学应用的流延和烧结 β-磷酸三钙层压板：研磨 A1203 纤维添加剂对微观结构和
DOI：
10.1002/jbm.b.32796
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Tanimoto Y,
中科院分区：
文献类型：
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作者：
Kawase T;Tanaka T;Okuda K;Tsuchimochi M;Oda M;Hara T.;Tanimoto Y,
本研究的目的是开发用于生物医学应用的带有研磨 Al2O3 纤维的流延、层压和烧结 β-磷酸三钙 (β-TCP)。此外，还研究了Al2O3纤维含量对烧结β-TCP层压板微观结构和机械性能的影响。将研磨后的 Al2O3 纤维以四种不同的含量（即 0、5、10 或 15 质量％）添加到初始 β-TCP 浆料中。接下来，通过流延法由含有研磨的 Al2O3 纤维的 β-TCP 浆料制备 β-TCP 生片。最后，将六层β-TCP单层片层压并在炉中在最高温度1100℃下烧结。结果表明，Al2O3纤维含量为0和5质量％的烧结β-TCP层合板的表观孔隙率、动态硬度和弯曲性能之间存在较大差异，而纤维含量为5、10和15质量％的层合板之间差异不大。这表明仅添加 5 质量％的 Al2O3 纤维就会强烈影响烧结程度，对应于 β-TCP 基体相的结晶。此外，当Al2O3纤维含量从5%变化到15%质量时，我们材料的弯曲模量在10.7到16.0 GPa之间，与其他研究人员报道的人体骨骼的弯曲模量几乎相同。总之，含有 Al2O3 纤维的烧结 β-TCP 层压板在广泛的生物医学应用中具有潜在用途，因为可以通过在 β-TCP 中添加 Al2O3 纤维来控制烧结 β-TCP 层压板的微观结构和机械性能。 © 2012 Wiley periodicals, Inc. J Biomed Mater Res B 部分：Appl Biomater，2012。
The aim of this study was to develop the tape‐cast, laminated, and sintered β‐tricalcium phosphate (β‐TCP) with milled Al2O3fibers for biomedical applications. Moreover, the effects of Al2O3‐fiber content on the microstructural and mechanical properties of the sintered β‐TCP laminates were investigated. The milled Al2O3fibers were added at four different contents, namely 0, 5, 10, or 15 mass%, to the initial β‐TCP slurry. Next, β‐TCP green sheets were fabricated from the β‐TCP slurry containing the milled Al2O3fibers by a tape‐casting method. Finally, six plies of β‐TCP monolayer sheet were laminated and sintered at a maximum temperature of 1100°C in a furnace. The results showed that there were large differences between the apparent porosities, dynamic hardness, and flexural properties of the sintered β‐TCP laminates with Al2O3‐fiber contents of 0 and 5 mass%, but few differences among laminates with fiber contents of 5, 10, and 15 mass%. This indicates that the addition of only 5 mass% of Al2O3fibers strongly affects the degree of sintering, corresponding to crystallization of the β‐TCP matrix phase. Furthermore, the flexural moduli of our materials ranged from 10.7 to 16.0 GPa when the Al2O3‐fiber content changed from 5 to 15 mass% and were the almost same as those of human bones reported by other researchers. In conclusion, sintered β‐TCP laminates with Al2O3fibers have potential uses in a wide range of biomedical applications because the microstructural and mechanical properties of the sintered β‐TCP laminates can be controlled by adding Al2O3fibers to the β‐TCP. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012.