Implementation Science in Thailand: Design and Methods of a Geriatric Mental Health Cluster-Randomized Trial.
Implementation Science in Thailand: Design and Methods of a Geriatric Mental Health Cluster-Randomized Trial.
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DOI：
10.1176/appi.ps.202000028
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发表时间：
2022-01-01
期刊：
影响因子：
--
通讯作者：
Marques AH
中科院分区：
文献类型：
--
作者：
Chen H;Levkoff S;Chuengsatiansup K;Sihapark S;Hinton L;Gallagher-Thompson D;Tongsiri S;Wisetpholchai B;Fritz S;Lamont A;Domlyn A;Wandersman A;Marques AH
泰国面临着人口迅速老龄化的问题，但缺乏有效和可扩展的循证心理社会干预措施的证据，以支持痴呆症患者及其家庭照顾者。在这项旨在减少老年人痴呆症（BPSD）行为和心理症状的文化适应和循证临床计划的研究中[减少阿尔茨海默病（RDAD）的残疾]，我们测试了实施支持策略[Getting-To-Outcomes®（GTO®）]的假设，与泰国背景下RDAD的通常实施相比，将显示更好的实施和临床结果。该研究采用混合III型随机分组设计，比较了接受RDAD临床干预和GTO实施支持策略培训的8个地理区域（干预组）与接受相同RDAD培训但未接受GTO实施支持策略培训的8个区域（对照组）。GTO是一种基于证据的干预措施，旨在为实施者提供实施支持，以便在新的环境中更好地计划，实施和评估创新干预方案。将在基线、第3个月（治疗后）和第6个月（3个月随访）评估主要结局，包括实施结局和临床结局。如果临床试验结果是积极的，我们计划复制和扩大拟议的实施科学方法，以加强和扩大泰国老年痴呆症患者的心理健康服务。
Thailand faces a rapidly aging population yet lacks evidence for effective and scalable evidence-based psychosocial interventions to support persons living with dementia and their family caregivers. In this study of a culturally-adapted and evidence-based clinical program designed to reduce behavioral and psychological symptoms of dementia (BPSD) in older adults [Reducing Disabilities in Alzheimer’s Disease (RDAD)], we test the hypothesis that an implementation support strategy [Getting-To-Outcomes®” (GTO®)] would show better implementation and clinical outcomes compared to usual implementation of RDAD in the Thai context. The study uses a hybrid type III cluster randomized design comparing 8 geographical districts (intervention arm) that receive training to implement both the RDAD clinical intervention and GTO implementation support strategies vs. 8 districts (control arm) that receive the same RDAD training without training in GTO implementation support strategies. GTO is an evidence-based intervention designed to provide implementation support for implementers to better plan, implement, and evaluate innovative intervention programs in a novel setting. Primary outcomes will be assessed at baseline, month 3 (post-treatment), and month 6 (3 month follow-up), including implementation outcomes and clinical outcomes. If clinical trial findings are positive, we plan to replicate and scale up the proposed implementation science approach to enhance and expand mental health services for older adults with dementia across Thailand.
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影响因子：
3
作者：
BERGNER, M;BOBBITT, RA;GILSON, BS
通讯作者：
GILSON, BS
影响因子：
7.2
作者：
Weiner, Bryan J.;Lewis, Cara C.;Halko, Heather
通讯作者：
Halko, Heather
影响因子：
6.3
作者：
Teri L;McCurry SM;Logsdon RG;Gibbons LE;Buchner DM;Larson EB
通讯作者：
Larson EB
影响因子：
5.7
作者：
Teri, Linda;Logsdon, Rebecca G.;McGough, Ellen L.
通讯作者：
McGough, Ellen L.
影响因子：
1.7
作者：
Chinman, Matthew;Acosta, Joie;Tellett-Royce, Nancy
通讯作者：
Tellett-Royce, Nancy