Her3 is associated with poor survival of gastric adenocarcinoma: Her3 promotes proliferation, survival and migration of human gastric cancer mediated by PI3K/AKT signaling pathway

Her3 is associated with poor survival of gastric adenocarcinoma: Her3 promotes proliferation, survival and migration of human gastric cancer mediated by PI3K/AKT signaling pathway
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Her3与胃腺癌生存不良相关:Her3通过PI3K/AKT信号通路介导促进人胃癌的增殖、生存和迁移

DOI:
10.1007/s12032-014-0903-x
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发表时间:
2014-03
期刊:
影响因子:
3.4
通讯作者:
Chen, Huanqiu
Chen, Huanqiu
中科院分区:
医学4区
文献类型:
--
作者:
Gu, Rongmin;Wen, Xu;Ming, Xuezhi;Chen, Huanqiu

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ErbB3(Her3)是一种膜结合蛋白,可与其他具有激酶活性的EGF受体家族成员形成异二聚体。先前的报道将Her3鉴定为人类胃癌(GC)中生存不良的显著预测因子,但其机制
ErbB3 (Her3) is a membrane-bound protein which can form heterodimers with other EGF receptor family members with kinase activity. Previous reports identified Her3 as a significant predictor of poor survival in human gastric cancer (GC), but its mechanism
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