The Talairach coordinate of a point in the MNI space: how to interpret it

The Talairach coordinate of a point in the MNI space: how to interpret it
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DOI:
10.1016/j.neuroimage.2004.12.007
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发表时间:
2005-04-01
期刊:
影响因子:
5.7
通讯作者:
McIntosh, AR
McIntosh, AR
中科院分区:
医学1区
文献类型:
--
作者:
Chau, W;McIntosh, AR

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为了使用功能成像数据进行群体研究,通常将单个脑图像转换到公共坐标空间。神经科学界使用最广泛的两个空间是Talairach空间和蒙特利尔神经研究所(MNI)空间。Talairach坐标系已成为科学出版物中报告大脑位置的标准参考,即使数据已在空间上转换为不同的大脑模板(例如,MNI空间)。当用单独的对象表示时,MNI空间中的坐标到Talairach空间的映射为不同的对象生成不同的坐标。在本文中,我们描述了两种从MNI空间获取Talairach坐标的方法,该方法基于国际脑图联合会的ICBM152模板。一种方法是在Afni软件包中实现的分段线性缩放的Talairach方法(TMPLS);另一种是使用SPM99中的线性变换的模板匹配方法。给出了测绘结果的不确定度测量结果。这可能会让研究人员更好地解释从MNI空间获得的Talairach坐标中的结果报告。这项研究还检查了Talairach坐标和从nmni2tal脚本获得的坐标之间的差异,nmni2tal脚本是神经成像社区常用的工具。下区、上额区和枕区差异较大。(C)2005 Elsevier Inc.保留所有权利。
To perform group studies using functional imaging data, the individual brain images are usually transformed into a common coordinate space. The two most widely used spaces in the neuroscience community are the Talairach space and the Montreal Neurological Institute (MNI) space. The Talairach coordinate system has become the standard reference for reporting the brain locations in scientific publication, even when the data have been spatially transformed into different brain templates (e.g., MNI space). When expressed in terms of individual subjects, the mapping of a coordinate in MNI space to the Talairach space generates distinct coordinates for different subjects. In this paper, we describe two approaches to derive the Talairach coordinates from the MNI space, which is based on the ICBM152 template from the International Consortium of Brain Mapping. One approach is the Talairach Method of Piecewise Linear Scaling (TMPLS) as implemented in the AFNI software package; and the other is a template-matching approach using the linear transformation in SPM99. The uncertainty measurements of the mapping results are presented. This may allow researchers to better interpret results reporting in the Talairach coordinates obtained from the MNI space. This study also examines the discrepancy between the derived Talairach coordinates and those obtained from the nmni2tal script, a tool commonly used by the neuroimaging community. Large discrepancies are found in the inferior regions, superior frontal and occipital regions. (c) 2005 Elsevier Inc. All rights reserved.