Effect of water aging on the anti-biofilm properties of glass ionomer cement containing fluoro-zinc-silicate fillers
Effect of water aging on the anti-biofilm properties of glass ionomer cement containing fluoro-zinc-silicate fillers
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DOI：
10.1080/08927014.2020.1856371
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发表时间：
2020-12-12
期刊：
影响因子：
2.7
通讯作者：
Noiri, Yuichiro
中科院分区：
文献类型：
--
作者：
Naksagoon, Traithawit;Ohsumi, Tatsuya;Noiri, Yuichiro
先前的一项研究报告称，一种新型氟锌硅酸盐玻璃离子水门汀（Caredyne Restore）通过干扰细菌粘附显示出上级抗生物膜效果。然而，活性离子可随时间降解。本研究旨在评估Caredyne Restore在水浸老化3周后的有效抗生物膜效果。变形链球菌生物膜被允许在水老化之前和之后的表面上生长24 h，使用改进的罗宾斯装置流动池系统。结果表明，水老化促进了挂膜。在中性pH条件下水老化后，Caredyne Restore释放的氟离子和锌离子量不足。需要酸性pH来发挥有效的抗生物膜性质。由于在修复后，从Caredyne Restore释放的活性离子将逐渐减少，修复可能无法阻止3周后的生物膜形成，而中性pH值通过唾液的缓冲能力维持。
A previous study has reported that a novel fluoro-zinc-silicate glass ionomer cement (Caredyne Restore) showed superior anti-biofilm effects by interfering with bacterial adhesion. However, the active ions may degrade with time. This study aimed to assess the valid anti-biofilm effects of Caredyne Restore after being aged by water immersion for 3 weeks. Streptococcus mutans biofilm was allowed to grow on the surface before and after water aging for 24 h using a modified Robbins device flow-cell system. The results showed water aging promoted biofilm formation. Insufficient amount of fluoride and zinc ions were released from Caredyne Restore after water aging under neutral pH condition. An acidic pH is needed to exert effective anti-biofilm properties. As the release of active ions from Caredyne Restore will gradually decrease after the restoration, the restoration may not prevent biofilm formation after 3 weeks while neutral pH is maintained by the buffering capacity of saliva.