Reactive grip force control in persons with cerebellar stroke: effects on ipsilateral and contralateral hand
Reactive grip force control in persons with cerebellar stroke: effects on ipsilateral and contralateral hand
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DOI：
10.1007/s00221-010-2203-9
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发表时间：
2010-05-01
影响因子：
2
通讯作者：
Hager-Ross, Charlotte
中科院分区：
文献类型：
--
作者：
Anens, Elisabeth;Kristensen, Bo;Hager-Ross, Charlotte
本研究通过检查（22-48岁）缺血性卒中（CL）所致局灶性小脑病变受试者与健康受试者（HS）之间的差异，探讨小脑对反应性抓握控制的贡献。受试者使用捏握来抓握并限制器械手柄在受到不同速率（2、4、8、32 N/s）或振幅（1、2、4 N）的不可预测载荷力时移动。小脑受试者病变同侧的手表现出延迟和更多变的反应延迟，例如，278 +/- A 162 ms（以2 N/s输送载荷），HS 180 +/- A 53 ms（P = 0.005）。CL还使用了比HS（1.3 +/- A 0.6 N）更高的同侧手预加载握力（1.6 +/-A 0.8 N）（P = 0.017）。此外，单侧小脑卒中受试者的对侧手与HS相比显示出延迟的抓握反应。因此，小脑病变损害了同侧和对侧手的反应性抓握控制。
This study investigates the cerebellar contribution to reactive grip control by examining differences between (22-48 years) subjects with focal cerebellar lesion due to ischaemic stroke (CL) and healthy subjects (HS). The subjects used a pinch grip to grasp and restrain an instrumented handle from moving when it was subject to unpredictable load forces of different rates (2, 4, 8, 32 N/s) or amplitudes (1, 2, 4 N). The hand ipsilateral to the lesion of the cerebellar subjects showed delayed and more variable response latencies, e.g., 278 +/- A 162 ms for loads delivered at 2 N/s, compared to HS 180 +/- A 53 ms (P = 0.005). The CL also used a higher pre-load grip force with the ipsilateral hand, 1.6 +/- A 0.8 N, than the HS, 1.3 +/- A 0.6 N (P = 0.017). In addition, the contralateral hand in subjects with unilateral cerebellar stroke showed a delayed onset of the grip response compared to HS. Cerebellar lesions thus impair the reactive grip control both in the ipsilateral and contralateral hand.