LOCOMOTION OF FIBROBLASTS IN CULTURE .1. MOVEMENTS OF LEADING EDGE
LOCOMOTION OF FIBROBLASTS IN CULTURE .1. MOVEMENTS OF LEADING EDGE
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DOI：
10.1016/0014-4827(70)90646-4
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发表时间：
1970-01-01
影响因子：
3.7
通讯作者：
PEGRUM, SM
中科院分区：
文献类型：
--
作者：
ABERCROMBIE, M;HEAYSMAN, JE;PEGRUM, SM
鸡胚心脏和新生小鼠肌肉成纤维细胞样细胞在平面上运动时，前缘上的任何一点都经历一个重复的突起和回缩过程，其长度约为5 μm，在数量上两种细胞非常相似。这种不规则的、可能很大程度上是随机的波动的平均持续时间约为4分钟。边缘也有静止期，同样不规则地发生，除了在撤退阶段很少发生之外;它们平均每8分钟一次。波动边缘的净向前位移不是由于向前运动的速度大于向后运动的速度，而是因为我们花了更多的时间向前而不是向后。在边缘上相隔6 μm的点处，运动具有高度的独立性。
During the locomotion on a plane surface of fibroblast-like cells from embryonic chick heart and neonatal mouse muscle, any point on the leading edge undergoes a repetitive protrusion and withdrawal, covering about 5 μm which is quantitatively very similar in the two kinds of cell. The average duration of this irregular, probably largely random fluctuation is about 4 min. There are also periods of standstill of the edge, again occurring irregularly except that they rarely occur during a phase of withdrawal; they average about one every 8 min. The net forward displacement of the fluctuating edge results, not from a greater speed of forward than of backward movement, but from a greater time spent moving forward than backward. There is a high degree of independence in movement at points 6 μm apart on the edge.