Determination and fate of oxytetracycline and related compounds in oxytetracycline production wastewater and the receiving river
Determination and fate of oxytetracycline and related compounds in oxytetracycline production wastewater and the receiving river
复制标题
DOI：
10.1897/07-080.1
复制
发表时间：
2008-01-01
影响因子：
4.1
通讯作者：
Li, Kuiziao
中科院分区：
文献类型：
--
作者：
Li, Dong;Yang, Min;Li, Kuiziao
采用高效电喷雾电离质谱仪(LC-ESI-MS)研究了土霉素(OTC)及其相关物质4-表土霉素(EOTC)、α-脱氧四环素(α-APO-OTC)和β-脱氧四环素(β-APO-OTC)在污水处理厂(WWTP)和污水处理厂出水河流中的存在和去向。处理后出水中OTC的平均去除率为38.0+/-10.5%，出水中OTC浓度仍可达19.5+/-2.9 mg/L。沿河浓度略有下降，R2点(排污点)为641+/-118 mg/L，R4点(距R2点20公里)为377+/-142 mg/L，仍高于报道的土霉素最低抑菌浓度(接近250mg/L)。另一方面，处理后的出水中其相关物质总量不到OTC的5%。α-载脂蛋白-OTC和β-载脂蛋白-OTC的浓度沿河流逐渐增加，从R2的5.76+/-0.63和2.08+/-0.30mU/L增加到R4的11.9+/-4.9和12.0+/-4.6mU/L，而EOTC则分别从31.5+/-3.8下降到12.9+/-1.1mU/L。河流沉积物中β-apo-CTC的平均浓度为20.8+/-7.8 mg/kg，其与OTC的比值约为0.11，几乎是α-apo-OTC和EOTC与OTC的比值(分别为0.058+/-0.014和0.061+/-0.015)的两倍。
This study investigated the occurrence and fate of oxytetracycline (OTC) and its related substances, 4-epi-oxytetracycline (EOTC), alpha-apo-oxytetracycline (alpha-apo-OTC), and beta-apo-oxytetracycline (beta-apo-OTC), in a wastewater treatment plant (WWTP) treating OTC production wastewater and a river receiving the effluent from the WWTP using liquid chromatography electrospray ionization mass spectrometry (LC-ESI-MS). The percent removal of OTC in the WWTP was 38.0 +/- 10.5%, and the concentration of OTC was still up to 19.5 +/- 2.9 mg/L in the treated outflow. The concentration slightly decreased along the river, from 641 +/- 118 mu g/L at site R2 (discharging point) to 377 +/- 142 mu g/L at site R4 (similar to 20 km from site R2), which was still higher than the minimal inhibition concentration of OTC reported (similar to 250 mu g/L). On the other hand, the total amount of its related substances in the treated effluent was less than 5% of OTC. Concentrations of alpha-apo-OTC and beta-apo-OTC increased along the river, from 5.76 +/- 0.63 and 2.08 +/- 0.30 mu g/L at site R2 to 11.9 +/- 4.9 and 12.0 +/- 4.6 mu g/L at R4, respectively, although EOTC decreased from 31.5 +/- 3.8 to 12.9 +/- 1.1 mu g/L, respectively. The mean concentration of beta-apo-CTC in river sediments was 20.8 +/- 7.8 mg/kg, and its ratio to OTC was approximately 0.11, nearly twice the ratio of alpha-apo-OTC and EOTC to OTC (0.058 +/- 0.014 and 0.061 +/- 0.015, respectively).