Total and soluble fluoride content in commercial dentifrices in Chile
Total and soluble fluoride content in commercial dentifrices in Chile
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DOI：
10.3109/00016357.2011.640287
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发表时间：
2012-12-01
影响因子：
2
通讯作者：
Cury, Jaime A.
中科院分区：
文献类型：
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作者：
Carrera, Carola A.;Giacaman, Rodrigo A.;Cury, Jaime A.
目标。无论牙膏中的氟化物总量(F)是多少，只有可溶部分具有防龋性，其浓度必须大于1000ppm。没有关于智利牙膏中F的质量的信息。因此，这项研究的目的是确定智利市售牙膏中的氟浓度。材料和方法：测试了五个不同品牌的18种牙膏，每种牙膏都是从智利三家不同的连锁药店购买的。对每种牙膏的总氟、总可溶性氟和离子氟浓度进行了评估，并以氟的百万分之(mug F/g)表示。结果。在被评估的牙膏中，77.8%的牙膏含有氟化钠(NaF)、16.7%的一氟磷酸盐(MFP)和5.6%的两种氟盐；77.2%的牙膏的总氟含量与制造商在标签上声明的相似，只有5种牙膏的浓度低于预期，超过了5%的不一致容差范围。全氟含量在958.8~1496.3 ppm之间，平均+/-SD为1270.5+/-183.7。有五种牙膏的总可溶性氟低于总氟，只有一种牙膏的可溶盐含量低于这类牙膏的推荐剂量。结论：大多数智利牙膏的可溶性氟含量在1000-1500 ppm范围内，因此可能具有防龋活性。
Objective. Regardless of the total amount of fluoride (F) in a dentifrice, only the soluble fraction presents anti-caries activity and its concentration must be above 1000 ppm. No information regarding the quality of F in Chilean toothpastes is available. The aim of this study, therefore, was to determine the F concentration present in commercially-available toothpastes in Chile. Materials and methods: Eighteen toothpastes of five different brands were tested, each purchased from three different chain drugstores in Chile. For each toothpaste, total, total soluble and ionic F concentrations were assessed and expressed as ppm of F (mu g F/g). Results. Among the dentifrices evaluated, 77.8% contained NaF (sodium fluoride), 16.7% MFP (monofluorphosphate) and 5.6% both types of F salts; 77.2% of the dentifrices showed similar total F content to that declared by the manufacturer in the labeling with only five with lower concentration than expected, beyond a 5% disagreement tolerance range. Total soluble F ranged from 958.8-1496.3 ppm (mean +/- SD: 1270.5 +/- 183.7). Five toothpastes showed lower total soluble F than total F. Only one toothpaste showed soluble salt levels below the recommended dose for this type of dentifrice. Conclusion: Most Chilean dentifrices evaluated contained soluble F within the range of 1000-1500 ppm and, therefore, may have anti-caries activity.