THE EFFECT OF COMPRESSIVE LOADING ON INTRAOSSEOUS PRESSURE IN THE FEMORAL-HEAD INVITRO
THE EFFECT OF COMPRESSIVE LOADING ON INTRAOSSEOUS PRESSURE IN THE FEMORAL-HEAD INVITRO
复制标题
DOI：
10.2106/00004623-198870060-00012
复制
发表时间：
1988-07-01
影响因子：
5.3
通讯作者：
TAGGART, R
中科院分区：
文献类型：
--
作者：
DOWNEY, DJ;SIMKIN, PA;TAGGART, R
我们使用材料试验机测量了20例人体尸体在连续施加载荷过程中的骨内压力。在四个不同的测试地点，压力与负载的上升严格成比例。在股骨头中，0.1秒内施加载荷的平均反应为55±。每980牛顿有66毫米汞柱。该值比髋臼头侧区域的平均反应高3.6倍，比股骨颈和股骨粗隆间区域的平均反应高2.6倍和2.8倍。在股骨头内的进一步研究中，在更快（0.03秒）和更慢（1.0秒）的加载时间下，压力分别增加了1.7和0.4倍。临床意义：体外加压载荷使股骨头关节旁松质骨受压。在体内，骨内压力的周期性变化可能在骨的重塑、灌注和负荷传递中发挥重要作用。此外，负荷引起的压力脉冲可能在非外伤性骨坏死的病因学中起作用。
We measured intraosseous pressures in twenty human hips from cadavera during progressive serial applications of load using a materials-testing machine. Pressure rose in strict proportion to load at each of four different testing sites. In the femoral head, the mean response to loads applied over 0.1 second was 55 .+-. 66 millimeters of mercury per 980 newtons. This value was 3.6 times higher than the mean response in a region cephalad to the acetabulum and 2.6 and 2.8 times higher than the mean response in the femoral neck and intertrochanteric regions. In further studies within the femoral head, pressures were accentuated and reduced by factors of 1.7 and 0.4, respectively, at faster (0.03 second) and slower (1.0 second) loading times. Clinical Relevance: The juxta-articular cancellous bone of the femoral head becomes pressurized with compressive loading in vitro. In vivo, cyclic changes in intraosseous pressure may play a major role in the remodeling, perfusion, and load transmission of bone. In addition, load-induced pressure pulses may have a role in the etiology of atraumatic osteonecrosis.