Antibacterial, physical and mechanical properties of flowable resin composites containing zinc oxide nanoparticles
Antibacterial, physical and mechanical properties of flowable resin composites containing zinc oxide nanoparticles
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DOI：
10.1016/j.dental.2013.03.011
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发表时间：
2013-05-01
期刊：
影响因子：
5
通讯作者：
Atai, Mohammad
中科院分区：
文献类型：
--
作者：
Hojati, Sara Tavassoli;Alaghemand, Homayoon;Atai, Mohammad
目标。本研究的目的是评价含纳米氧化锌的树脂复合材料对变形链球菌的抑菌活性，并检测其物理机械性能。通过不同的测试来研究含0-5wt.%纳米氧化锌的流动树脂复合材料的性能：a.抗菌活性(包括对固化树脂的琼脂扩散试验，液体介质中细菌的直接接触试验，评估样品在液体介质中的老化效果，以及扫描电子显微镜(SEM)).b.力学行为(包括弯曲、压缩强度和弹性模量).c.固化方面(包括固化深度和转化率).D.粘接性能(包括微剪切粘结强度)。虽然琼脂扩散试验显示两组之间没有显著差异，但直接接触试验表明，随着纳米颗粒含量的增加，细菌的生长显著减少(p<；0.05)。然而，在老化试验中，抗菌性能显著降低(p<；0.05)。纳米颗粒(p>；0.05)的加入使复合材料的弯曲强度和压缩弹性模量保持不变，而压缩强度和弯曲弹性模量显着增加(p<；0.05)。含有氧化锌的树脂具有较低的固化深度(p<；0.05)和较高的粘接强度(p<；0.05)。FTIR技术测定的转化度在两组间无显著差异(p>；0.05)。在牙科材料科学中，生产一种具有抗菌活性而不会对机械性能产生显著影响的牙科树脂复合材料是可取的。(C)2013年牙科材料学会。爱思唯尔有限公司出版。保留所有权利。
Objectives. The aim of this study is evaluating the antibacterial activity of resin composites containing ZnO nanoparticles against Streptococcus mutans and examining their physical and mechanical properties.Methods. The properties of flowable resin composites containing 0-5 wt.% nano-ZnO are investigated using different tests:A. Antibacterial activity (including agar diffusion test on the cured resins, direct contact test using bacteria in a liquid medium, evaluating the effect of aging while the samples are adjacent to a liquid medium, and scanning electron microscopy (SEM)).B. Mechanical behavior (including flexural and compressive strength and modulus).C. Curing aspects (including depth of cure and degree of conversion).D. Adhesion properties (including micro-shear bond strength).Results. Although the agar diffusion test reveals no significant difference between the groups, the direct contact test demonstrates that by increasing the nanoparticle content, the bacterial growth is significantly diminished (p < 0.05). In the aging test, however, the antibacterial properties reduce significantly (p < 0.05). The flexural strength and compressive modulus remains unchanged by incorporation of nanoparticles (p > 0.05) while the compressive strength and flexural modulus significantly increase (p < 0.05). The ZnO containing resins show significantly lower depth of cure (p < 0.05), and higher bond strength (p < 0.05). There is no significant difference between the degrees of conversion, measured by FTIR technique, of the groups (p > 0.05).Significance. Production of a dental resin composite with antibacterial activity without significant sacrificing effect on the mechanical properties is desirable in dental material science. (C) 2013 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.