Candida albicans acid proteinase: characterization and role in candidiasis.
Candida albicans acid proteinase: characterization and role in candidiasis.
复制标题
白色念珠菌酸性蛋白酶：特征及其在念珠菌病中的作用。
DOI：
10.1007/978-1-4684-6012-4_22
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发表时间：
1991
影响因子：
--
通讯作者：
Morrow,BJ
中科院分区：
文献类型：
--
作者：
Ray,TL;Payne,CD;Morrow,BJ
白色念珠菌和相关物种是医学上重要的酵母样二态真菌，在免疫功能低下和衰弱的患者中，它们是造成严重、危及生命的机会性感染发病率上升的部分原因。除了皮肤、口咽和阴道上皮的轻微局部感染外，念珠菌。产生短暂或持续的真菌血症，导致几乎任何器官（尤其是肝脏、肾脏和肺）的全身感染。患有长期中性粒细胞减少症和抗生素耐药性发热的血液恶性肿瘤和移植患者尤其面临风险。白色念珠菌 C.热带物种在医学上是最重要的，尽管其他物种确实会引起疾病，但频率较低。
Candida albicansand related species are medically important yeast-like dimorphic fungi that are responsible, in part, for the rising incidence of serious, life-threatening opportunistic infections seen in immunocompromised and debilitated patients. In addition to minor localized infections of cutaneous, oropharyngeal and vaginal epithelium,Candidaspp. produce transient or persistent fungemia that leads to systemic infections of virtually any organ (esp. liver, kidney and lung). Hematologic malignancy and transplant patients with prolonged neutropenia and antibiotic resistant fevers are particularly at risk.C. albicansandC. tropicalisare medically the most important, although other species do cause disease, but less frequently.