Non-linear dynamics of electrocardiographic waveforms following cocaine administration.

Non-linear dynamics of electrocardiographic waveforms following cocaine administration.
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可卡因给药后心电图波形的非线性动力学。

DOI:
10.1016/0024-3205(91)90153-3
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发表时间:
1991
期刊:
影响因子:
6.1
通讯作者:
Harper,RM
Harper,RM
中科院分区:
医学2区
文献类型:
--
作者:
Garfinkel,AJ;Walter,DO;Trelease,RB;Harper,RK;Harper,RM

文献摘要

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We examined dynamics of ECG waveforms preceding and following 10mg/kg intravenous administration of cocaine in freely moving cats. Cocaine induced substantial variation in ECG waveforms, as demonstrated by non-linear procedures of phase-plane plots and Poincaré analyses. Phase-plane plots revealed that waveform variation following cocaine administration was not randomly or uniformly distributed, but instead followed patterns of clustered organization with unvisited regions. These patterns are characteristic of chaotic distributions, and support the hypothesis that ECG waveform variation following cocaine does not degenerate into random patterns; instead, the variation follows deterministic, though chaotic patterns.