A preliminary study of the kiddie schedule for affective disorders and schizophrenia for school-age children mania rating scale for children and adolescents
A preliminary study of the kiddie schedule for affective disorders and schizophrenia for school-age children mania rating scale for children and adolescents
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DOI：
10.1089/104454603322724850
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发表时间：
2003-12-01
影响因子：
1.9
通讯作者：
Ryan, N
中科院分区：
文献类型：
--
作者：
Axelson, D;Birmaher, BJ;Ryan, N
目的：方法：采用1986年版儿童情感障碍和精神分裂症量表（K-SADS-P）中的14个问题，加上一个新的评定心境不稳定性的项目，编制临床医师评定的躁狂评定量表（K-SADS-MRS）。前瞻性地确定了22例来自双相情感障碍门诊的患者的评估者间可靠性。在一个单独的队列的23 patients.Results：内部一致性（Cronbach的α = 0.94）和评价者之间的可靠性（两个评价者之间的组内相关系数= 0.97）的敏感性治疗效果进行了测定。临床总体印象-严重程度量表（双极版）的收敛效度良好（r（s）= 0.91，p < 0.001）。治疗应答者的K-SADS-MRS评分比无应答者显著降低（-15.6 +/- 8.7 vs. 0.3 +/- 8.8），t（21）= 4.2，p < 0.001。结论：K-SADS-MRS评分可作为评估儿童双相情感障碍躁狂症状严重程度的一种方法，其敏感性为87%，特异性为81%。
Objective: To construct a mania rating scale designed for children and adolescents.Methods: Fourteen questions from the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present Episode (K-SADS-P) 1986 version plus a new item assessing mood lability were used to construct a clinician-rated mania rating scale (K-SADS-MRS). Interrater reliability was determined prospectively with 22 patients from a bipolar outpatient clinic. Sensitivity to treatment effects was determined in a separate cohort of 23 patients.Results: Internal consistency (Cronbach's alpha = 0.94) and interrater reliability (intraclass correlation coefficient = 0.97 between two raters) were high. Convergent validity with the Clinical Global Impressions-Severity scale (bipolar version) was good (r(s) = 0.91, p < 0.001). Treatment responders had significantly greater reduction in K-SADS-MRS scores than non-responders (-15.6 +/- 8.7 vs. 0.3 +/- 8.8), t(21) = 4.2, p < 0.001. The K-SADS-MRS scores differentiated bipolar patients who had clinically significant manic symptoms from those who did not, with a sensitivity of 87% and a specificity of 81%.Conclusion: The K-SADS-MRS shows promise as a rating scale for measuring manic symptom severity in pediatric bipolar patients.