Functional Analysis of Insertion Sequence ISAba1, Responsible for Genomic Plasticity of Acinetobacter baumannii
Functional Analysis of Insertion Sequence ISAba1, Responsible for Genomic Plasticity of Acinetobacter baumannii
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DOI：
10.1128/jb.01258-08
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发表时间：
2009-04-01
影响因子：
3.2
通讯作者：
Nordmann, Patrice
中科院分区：
文献类型：
--
作者：
Mugnier, Pauline D.;Poirel, Laurent;Nordmann, Patrice
ISAba1是广泛分布于鲍曼不动杆菌中的插入序列。我们在此证明 ISAba1 和复合转座子 Tn2006 能够转座，产生 9 bp 的靶位点重复。 ISAba1 转座酶编码基因的表达通过翻译移码而下调。
ISAba1 is an insertion sequence that is widely distributed in Acinetobacter baumannii. We demonstrated here that ISAba1 and the composite transposon Tn2006 are capable of transposition, generating 9-bp target site duplications. The expression of the ISAba1 transposase-encoding gene was downregulated by translational frameshifting.