Construction and characterization of a high-flow, high-resolution ion mobility spectrometer for detection of explosives after personnel portal sampling
Construction and characterization of a high-flow, high-resolution ion mobility spectrometer for detection of explosives after personnel portal sampling
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DOI：
10.1016/s0039-9140(01)00680-4
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发表时间：
2002-04-22
期刊：
影响因子：
6.1
通讯作者：
Hill, HH
中科院分区：
文献类型：
--
作者：
Wu, C;Steiner, WE;Hill, HH
首次展示了一种通过航空旅客人员门户与高流量（HF）、高分辨率（HR）离子迁移谱法（IMS）耦合分析爆炸物的新方法。HF-HR-IMS采用新颖的离子孔径网格设计和Ni-63电离源，在200℃的环境压力下以正离子模式工作。研究了2,4,6-三硝基甲苯（TNT）、4,6-二硝基邻甲酚（4,6dnoc）和环-1,3,5-三亚甲基-2,4,6-三硝胺（RDX）对HF-HR-IMS的响应特性。对HF-HR-IMS排气和电离源的改进使总离子电流（TIC）增加了800%，从0.85 nA增加到6.8 nA。与传统的IMS相比，这意味着TNT的离子响应增加了65%。用TNT和（4,6 dnoc）的混合物成功地证明了具有相似降低迁移常数（K-o）的物种的分辨能力，分别为1.54和1.59。当三种不同孔径的内径从1.00到3.54cm变化时，反应物离子（H2O）(n)H+的峰也被用来测量光谱仪的分辨能力。这提供了50-60的分辨率范围，是商用IMS仪器通常可实现的两倍。最重要的是，这种新仪器设计中的这些变化可以应用于所有现有和未来的IMS，从而大大提高可实现的IMS解析能力。(C) 2002 Elsevier Science B.V.版权所有
A novel analysis of explosives via the coupling of an airline passenger personnel portal with a high-flow (HF), high-resolution (HR) ion mobility spectrometry (IMS) was shown for the first time. The HF-HR-IMS utilized a novel ion aperture grid design with a Ni-63 ionization source while operating at ambient pressure in the positive ion mode at 200 degreesC. The HF-HR-IMS response characteristics of 2,4,6-trinitrotoluene (TNT), 4,6-dinitro-o-cresol (4,6DNOC), and cyclo-1,3,5-trimethylene-2,4,6-trinitramine (RDX) were investigated. Modifications made to the HF-HR-IMS exhaust and ionization source created an 800% increase in the total ion current (TIC), from 0.85 to 6.8 nA. This translated into a 65% ion response increase for TNT when compared with a traditional IMS. A mixture of TNT and (4,6DNOC) was used to successfully demonstrate the resolving power of the species with similar reduced mobility constants (K-o), 1.54 and 1.59, respectively. The reactant ion (H2O)(n)H+, peak was also used to measure the resolving power of the spectrometer while varying the internal diameter of three different aperture openings from 1.00 to 3.54cm. This provided a resolving power range of 50-60, double that typically achievable by commercial IMS instruments. Most important, these changes made in this new instrumental design can be implemented to all existing and future IMS's to greatly enhance the achievable IMS resolving power. (C) 2002 Elsevier Science B.V. All rights reserved.