?-TuRCs

?-TuRCs
复制标题

?-TuRC

DOI:
10.1016/j.cub.2019.04.013
复制
发表时间:
2019
期刊:
影响因子:
9.2
通讯作者:
Mukherjee A
Mukherjee A
中科院分区:
生物学1区
文献类型:
--
作者:
Mukherjee A

文献摘要

相似文献

什么是γ-TuRCs?γ-微管蛋白环复合物(γ-TuRC)是多蛋白复合物,催化细胞中新微管的动力学不利形成(图1)。它们通常在微管组织中心(MTOC)被招募和激活,例如有丝分裂期间的中心体或肌肉细胞中的核被膜。微管成核的这种时空调节允许不同的细胞类型控制特定功能所需的特定微管阵列的形成。
What are γ-TuRCs? γ-tubulin ring complexes (γ-TuRCs) are multi-protein complexes that catalyse the kinetically unfavourable formation of new microtubules in cells (Figure 1). They are typically recruited and activated at microtubule-organising centres (MTOCs), such as the centrosome during mitosis or the nuclear envelope in muscle cells. This spatiotemporal regulation of microtubule nucleation allows different cell types to control the formation of particular microtubule arrays necessary for specific functions.