?-TuRCs
?-TuRCs
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?-TuRC
DOI:
10.1016/j.cub.2019.04.013
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发表时间:
2019
期刊:
影响因子:
9.2
通讯作者:
Mukherjee A
中科院分区:
文献类型:
--
作者:
Mukherjee A
What are γ-TuRCs? γ-tubulin ring complexes (γ-TuRCs) are multi-protein complexes that catalyse the kinetically unfavourable formation of new microtubules in cells (Figure 1). They are typically recruited and activated at microtubule-organising centres (MTOCs), such as the centrosome during mitosis or the nuclear envelope in muscle cells. This spatiotemporal regulation of microtubule nucleation allows different cell types to control the formation of particular microtubule arrays necessary for specific functions.