The blocked pinocytic activity of mitotic cells is restored in mitotic-interphase hybrids.
The blocked pinocytic activity of mitotic cells is restored in mitotic-interphase hybrids.
复制标题
有丝分裂细胞受阻的胞饮活性在有丝分裂间期杂交中得到恢复。
DOI：
10.1016/0014-4827(87)90178-9
复制
发表时间：
1987
影响因子：
3.7
通讯作者：
Seagrave,JC
中科院分区：
文献类型：
--
作者：
Oliver,JM;Seagrave,JC
During mitosis there is an abrupt inhibition of a wide range of membrane functions, including fluid-phase and adsorptive pinocytosis. We have used cell hybrids formed between mitotic and interphase cells to approach the mechanism of this inhibition. We report that fluid pinocytosis is reactivated in the mitotic partner of hybrids formed between mitotic and interphase Chinese hamster ovary (CHO) cells. It thus appears that the interphase cell provides some necessary element(s) for membrane activity during mitosis. This dominance of interphase membrane properties stands in contrast with earlier evidence that mitotic nuclear properties dominate in similar mitotic—interphase hybrids.
