Seasonal pattern of hepatitis E virus prevalence in swine in two different geographical areas of China.
Seasonal pattern of hepatitis E virus prevalence in swine in two different geographical areas of China.
复制标题
中国两个不同地理区域猪戊型肝炎病毒流行的季节特征
DOI：
10.1017/s0950268813000113
复制
发表时间：
2013-11
影响因子：
4.2
通讯作者：
Zheng, Y. J.
中科院分区：
文献类型：
--
作者：
Lu, Y. H.;Qian, H. Z.;Hu, A. Q.;Qin, X.;Jiang, Q. W.;Zheng, Y. J.
我们研究了中国猪戊型肝炎病毒（HEV）感染的季节特征。从2008年到2011年，收集了4200份猪胆汁标本用于检测HEV RNA。中国东部和西南地区分别有3.83%（92/2400）和2.61%（47/1800）的样本呈HEV阳性。提出了不同地理区域的季节模式。在中国东部地区，3 - 4月为HEV RNA流行高峰，9 - 10月为小高峰，7 - 8月呈下降趋势。西南地区9 - 10月为高峰，3 - 4月为低谷。4a亚型病例最多（76.83%,63/82）集中在上半年，4b亚型病例最多（89.66%,26/29）集中在下半年，不同亚型发病高峰不同。我们的研究结果表明，HEV亚型的分布与季节模式有关。
We studied seasonal patterns of swine hepatitis E virus (HEV) infection in China. From 2008 through 2011, 4200 swine bile specimens were collected for the detection of HEV RNA. A total of 3.83% (92/2400) of specimens in eastern China and 2.61% (47/1800) in southwestern China were positive for HEV. Seasonal patterns differing by geographical area were suggested. In eastern China, the major peak of HEV RNA prevalence was during March-April, with a minor peak during September-October, and a dip during July-August. In southwestern China, the peak was during September-October and the dip during March-April. The majority of subtype 4a cases (76.83%, 63/82) were detected in the first half of the year, while the majority of subtype 4b cases (89.66%, 26/29) were concentrated in the second half of the year, suggesting different subtype contribute to different peaks. Our results indicate that the distribution of HEV subtypes is associated with seasonal patterns.