Effects of yoga in adults with type 2 diabetes mellitus: A meta-analysis.
Effects of yoga in adults with type 2 diabetes mellitus: A meta-analysis.
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DOI：
10.1111/jdi.12548
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发表时间：
2017-03
影响因子：
3.2
通讯作者：
Guo YZ
中科院分区：
文献类型：
--
作者：
Cui J;Yan JH;Yan LM;Pan L;Le JJ;Guo YZ
进行了一项Meta分析，以评估瑜伽对2型糖尿病成人的疗效。检索PubMed、EMBASE和科克伦数据库，以获得合格的随机对照试验。主要结局为空腹血糖，次要结局包括糖化血红蛋白A1 c、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、甘油三酯和餐后血糖。计算加权平均差异和95%置信区间（CI）。I2统计量代表异质性。共有12项随机对照试验（共864例患者）符合纳入标准。空腹血糖和血红蛋白A1 c的合并加权平均差异分别为−23.72 mg/dL（95% CI −37.78至−9.65; P = 0.001; I 2 = 82%）和−0.47%（95% CI −0.87至−0.07; P = 0.02; I 2 = 82%）。加权平均差异为-17.38 mg/dL（95% CI −27.88至−6.89; P = 0.001; I 2 = 0%）餐后血糖为−18.50 mg/dL（95% CI −29.88至−7.11; P = 0.001; I 2 = 75%）总胆固醇为4.30 mg/dL（95% CI 3.25至5.36; P < 0.00001; I 2 = 10%）高密度脂蛋白胆固醇，−12.95 mg/dL低密度脂蛋白胆固醇（95% CI −18.84至−7.06; P < 0.0001; I2 = 37%）和甘油三酯（−12.57 mg/dL）（95% CI −29.91至4.76; P = 0.16; I2 = 48%）。现有的证据表明，瑜伽有益于2型糖尿病成人患者。然而，考虑到有限的方法和潜在的异质性，需要进一步的研究来支持我们的研究结果，并调查瑜伽对2型糖尿病患者的长期影响。
A meta‐analysis was carried out to evaluate the efficacy of yoga in adults with type 2 diabetes mellitus. The PubMed, EMBASE and Cochrane databases were searched to obtain eligible randomized controlled trials. The primary outcome was fasting blood glucose, and the secondary outcomes included glycosylated hemoglobin A1c, total cholesterol, high‐density lipoprotein cholesterol, low‐density lipoprotein cholesterol, triglyceride and postprandial blood glucose. Weighted mean differences and 95% confidence intervals (CIs) were calculated. The I 2 statistic represented heterogeneity. A total of 12 randomized controlled trials with a total of 864 patients met the inclusion criteria. The pooled weighted mean differences were −23.72 mg/dL (95% CI −37.78 to −9.65; P = 0.001; I 2 = 82%) for fasting blood glucose and −0.47% (95% CI −0.87 to −0.07; P = 0.02; I 2 = 82%) for hemoglobin A1c. The weighted mean differences were −17.38 mg/dL (95% CI −27.88 to −6.89; P = 0.001; I 2 = 0%) for postprandial blood glucose, −18.50 mg/dL (95% CI −29.88 to −7.11; P = 0.001; I 2 = 75%) for total cholesterol, 4.30 mg/dL (95% CI 3.25 to 5.36; P < 0.00001; I 2 = 10%) for high‐density lipoprotein cholesterol, −12.95 mg/dL (95% CI −18.84 to −7.06; P < 0.0001; I 2 = 37%) for low‐density lipoprotein cholesterol and −12.57 mg/dL (95% CI −29.91 to 4.76; P = 0.16; I 2 = 48%) for triglycerides. The available evidence suggests that yoga benefits adult patients with type 2 diabetes mellitus. However, considering the limited methodology and the potential heterogeneity, further studies are necessary to support our findings and investigate the long‐term effects of yoga in type 2 diabetes mellitus patients.