ASSOCIATION AND COMMISSURAL FIBER SYSTEMS OF OLFACTORY CORTEX OF RAT .2. SYSTEMS ORIGINATING IN OLFACTORY PEDUNCLE
ASSOCIATION AND COMMISSURAL FIBER SYSTEMS OF OLFACTORY CORTEX OF RAT .2. SYSTEMS ORIGINATING IN OLFACTORY PEDUNCLE
复制标题
DOI：
10.1002/cne.901810407
复制
发表时间：
1978-01-01
影响因子：
2.5
通讯作者：
PRICE, JL
中科院分区：
文献类型：
--
作者：
HABERLY, LB;PRICE, JL
观察嗅脚内各区域（嗅前核和顶盖带）的结构和联系。嗅前核分为外侧、外侧、背侧、内侧和腹后部。所有包含与顶端和基底树突定向正常的表面，基本上是皮质的组织中的神经元型细胞。利用辣根过氧化物酶（HRP）的逆行和顺行轴突运输的实验表明，这些部分的前嗅核具有独特的模式与其他嗅觉区的传入和传出连接。所有的分支都有向同侧和对侧的投射，尽管同侧的外侧部（向嗅球）的投射非常轻。交叉投影在每种情况下主要指向与同伦区域相邻的区域。在tenia tecta中也可以区分两个主要的亚部：背侧部分主要由紧密排列的神经元组成，这些神经元非常类似于齿状回的颗粒细胞（浓密的顶端树突，但没有基底树突），腹侧部分主要包含齿状回型细胞。这两个部分的连接也非常不同。腹侧被盖接受来自嗅球、前嗅核外侧部、梨状皮质和外侧内嗅区的重要投射。它向外侧部发出较重的返回投射，向嗅球、梨状皮质和嗅结节发出较轻的投射。背侧覆盖带接受梨状皮质的重投射，但没有来自嗅球的投射。背侧tenia tecta的几个细胞逆行标记从HRP注射到内侧的嗅脚（涉及腹侧tenia tecta和邻近地区），但没有标记从其他嗅区注射。嗅脚背侧的一个区域被称为背脚皮层。这个区域最显著的特征是它与内嗅皮层有非常紧密的相互联系，尽管它也与嗅球和梨状皮层有紧密的联系，并突出到嗅结节。在嗅脚的内侧和腹侧的第一层的细胞已被逆行标记从HRP注射到嗅结节和外侧下丘脑区。这些细胞覆盖腹侧tenia tecta，内侧部分的前梨状皮质和pars腹后和pars外侧的前嗅核，但似乎没有分布在cytoarchitectonic边界。本文还讨论了嗅脚内各区可能的功能作用。
The structure and connections of areas within the olfactory peduncle (anterior olfactory nucleus and tenia tecta) were examined. The anterior olfactory nucleus was divided into external, lateral, dorsal, medial and ventro-posterior parts. All contained pyramidal-type cells with apical and basal dendrites oriented normal to the surface, and essentially cortical in organization. Experiments utilizing retrograde and anterograde axonal transport of horseradish peroxidase (HRP) demonstrated that each of these parts of the anterior olfactory nucleus possesses a unique pattern of afferent and efferent connections with other olfactory areas. All subdivisions have projections to both the ipsilateral and contralateral sides, although the ipsilateral projection of the pars externa (to the olfactory bulb) is extremely light. Crossed projections are in each case directed predominantly to areas adjacent to the homotopic areas. Two primary subdivisions may also be distinguished in the tenia tecta: a dorsal part composed largely of tightly packed neurons which closely resemble the granule cells of the dentate gyrus (bushy apical but no basal dendrites) and a ventral part which contains predominantly pyramidal-type cells. The connections of these 2 parts are also very different. The ventral tenia tecta receives substantial projections from the olfactory bulb, pars lateralis of the anterior olfactory nucleus, piriform cortex and lateral entorhinal area. It gives off a heavy return projection to the pars lateralis and lighter projections to the olfactory bulb, piriform cortex and olfactory tubercle. The dorsal tenia tecta receives a heavy projection from the piriform cortex, but none from the olfactory bulb. A few cells in the dorsal tenia tecta are retrogradely labeled from HRP injections into the medial aspect of the olfactory peduncle (involving the ventral tenia tecta and adjacent areas), but none are labeled from the other olfactory areas that were injected. An area on the dorsal aspect of the olfactory peduncle was termed the dorsal peduncular cortex. The most striking feature of this area is its very heavy reciprocal connection with the entorhinal cortex, although it is also reciprocally connected with the olfactory bulb and piriform cortex and projects to the olfactory tubercle. Cells in layer I of the medial and ventral aspects of the olfactory peduncle have been retrogradely labeled from HRP injections into the olfactory tubercle and lateral hypothalamic area. These cells overlie the ventral tenia tecta, medial part of the anterior piriform cortex and pars ventro-posterior and pars lateralis of the anterior olfactory nucleus, but do not appear to be distributed in relation to the cytoarchitectonic boundaries. Possible functional roles of the areas within the olfactory peduncle were discussed.