The influence of marital status and partner concordance on participation in colorectal cancer screening
The influence of marital status and partner concordance on participation in colorectal cancer screening
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DOI：
10.1093/eurpub/ckaa206
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发表时间：
2021-04-01
影响因子：
4.4
通讯作者：
Tybjerg, Anne Julie
中科院分区：
文献类型：
--
作者：
Gram, Mie Agermose;Therkildsen, Christina;Tybjerg, Anne Julie
背景：使用粪便免疫化学测试的结直肠癌筛查计划旨在通过早期发现降低发病率和死亡率。虽然参加筛查是免费的，但几乎有40%的被邀请者选择不参加。为了对如何识别和定位不参与提供新的见解，我们研究了婚姻状况和参与筛查之间的关系；重点关注伴侣在参与和性别差异方面的一致性。方法：这项全国性的横断面研究包括所有年龄在50-74岁之间的丹麦公民，他们被邀请在2014年至2017年期间进行结直肠癌筛查。在调整社会人口变量后，采用Logistic回归分析估计参与的优势比（OR）。结果：共纳入1 909 662人，其中62.7%的人参加了筛查计划。妇女的参与率最高。按婚姻状况分层，丧偶（61.5%）、离婚（54.8%）和单身（47.3%）的筛查参与率明显较低，而已婚个体的筛查参与率为68.4%。与已婚者相比，寡妇的or值为0.59 (95% CI 0.58-0.59)，离婚的or值为0.56 (95% CI 0.55-0.56)，单身的or值为0.47 （95% CI 0.47-0.48）。无论性别如何，有伴侣的已婚人士参与研究的可能性是没有伴侣的已婚人士的五倍。结论：婚姻状况与结直肠癌筛查的参与程度密切相关，已婚且有伴侣参与的人群参与程度更高。考虑到伴侣一致性的作用，未来增加结直肠癌筛查参与的努力可能会受益。
Background: Colorectal cancer screening program using a fecal immunochemical test aims to reduce morbidity and mortality through early detection. Although screening participation is free-of-charge, almost 40% of the invited individuals choose not to participate. To bring new insight into how non-participation can be identified and targeted, we examined the association between marital status and screening participation; with a focus on partner concordance in participation and sex differences. Methods: This nationwide cross-sectional study included all Danish citizens aged 50-74years, who were invited to colorectal cancer screening between 2014 and 2017. Logistic regression analysis was used to estimate odds ratio (OR) of participation while adjusting for sociodemographic variables. Results: A total of 1 909 662 individuals were included in the analysis of which 62.7% participated in the screening program. Participation was highest among women. Stratified by marital status, screening participation was markedly lower in widowed (61.5%), divorced (54.8%) and single (47.3%), while participation reached 68.4% in married individuals. This corresponded to ORs of 0.59 (95% CI 0.58-0.59) for widowed, 0.56 (95% CI 0.55-0.56) for divorced and 0.47 (95% CI 0.47-0.48) for single, compared to married individuals. Individuals married to a participating partner were five times more likely to participate than married individuals with a non-participating partner, regardless of gender. Conclusions: Marital status was strongly associated with participation in colorectal cancer screening, and participation was even higher in married individuals with a participating partner. Future efforts to increase participation in colorectal cancer screening could potentially benefit from considering the role of partner concordance.