Risk factors for the acquisition of genital warts: are condoms protective?
Risk factors for the acquisition of genital warts: are condoms protective?
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DOI：
10.1136/sti.75.5.312
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发表时间：
1999-10-01
影响因子：
3.6
通讯作者：
Mindel, A
中科院分区：
文献类型：
--
作者：
Wen, LM;Estcourt, CS;Mindel, A
目的：为了预防生殖器疣的风险因素，特别是要确定是否避孕套赋予保护免受infection.Methods：一项回顾性病例对照研究比较人口，行为和性因素的男性和女性，并没有新诊断的生殖器疣，谁出席悉尼性健康中心（SSHC），内城公共性健康中心，在1996年。从SSHC数据库中提取数据。结果：共纳入疣患者977例，对照组977例，按性别和就诊时间配对。单变量分析显示，在男性和女性中，年龄较小、终生性伴侣较多、不使用避孕套、吸烟和饮酒较多与疣相关，与既往感染沙眼衣原体、淋病奈瑟菌、B型肝炎和生殖器疱疹呈负相关。在男性中，多变量分析，仍然显着的因素是年轻的年龄，更多的终身性伴侣，不使用避孕套，更多的吸烟，和以前的衣原体感染。在妇女中，仍然显着的因素是年轻的年龄，更多的终身性伴侣，避孕套的使用，婚姻状况，和以前感染沙眼衣原体和herpes.Conclusions：生殖器疣的独立危险因素包括年轻，更多的终身性伴侣，吸烟。坚持使用避孕套可显著降低患生殖器疣的风险。
Objectives: To characterise risk factors for the acquisition of genital warts and specifically to determine whether condoms confer protection from infection.Methods: A retrospective case-control study comparing demographic, behavioural, and sexual factors in men and women with and without newly diagnosed genital warts, who attended Sydney Sexual Health Centre (SSHC), an inner city public sexual health centre, in 1996. Data were extracted from the SSHC database. Crude odds ratios (OR) were calculated to compare cases and controls and significant factors were then controlled for using multivariate logistic regression to obtain adjusted odds ratios (ORs).Results: 977 patients with warts and 977 controls matched by sex and date of attendance were included. In both sexes, univariate analysis revealed that younger age, more lifetime sexual partners, failure to use condoms, greater cigarette smoking and alcohol consumption were associated with warts, and there was a negative association with previous infection with Chlamydia trachomatis, Neisseria gonorrhoeae, hepatitis B, and genital herpes. In males, on multivariate analysis, factors which remained significant were younger age, more lifetime sexual partners; failure to use condoms, greater cigarette smoking, and previous chlamydia. In women, factors which remained significant were younger age, more lifetime sexual partners, condom use, marital status, and previous infections with Chlamydia trachomatis and herpes.Conclusions: Independent risk factors for genital warts include younger age, greater number of lifetime sexual partners, and smoking. Consistent condom use significantly reduces the risk of acquiring genital warts.