Facial emotion processing in criminal psychopathy - Preliminary functional magnetic resonance imaging study
Facial emotion processing in criminal psychopathy - Preliminary functional magnetic resonance imaging study
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DOI：
10.1192/bjp.bp.106.021410
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发表时间：
2006-12-01
影响因子：
10.5
通讯作者：
Murphy, Declan G.
中科院分区：
文献类型：
--
作者：
Deeley, Quinton;Daly, Eileen;Murphy, Declan G.
有研究认为，精神病患者缺乏同理心是因为他们在处理痛苦线索（如恐惧的面部表情）方面存在缺陷。目的探讨精神病患者和对照组处理面部情绪时的脑功能。方法采用事件相关功能磁共振成像技术，对6名在《哈雷精神变态量表》上得分>= 25分的受试者和9名非精神变态的健康志愿者在使用恐惧、快乐和中性面孔进行内隐情绪加工任务时进行比较。结果精神变态组在处理两种面部情绪时梭状回和纹外皮层的激活均明显低于对照组。然而，情绪类型影响反应模式。与中性面孔相比，两组在处理快乐面孔时梭状回和外纹层皮层的激活都有所增加，但这种增加在精神病态组中明显较小。与中性面孔相比，在处理恐惧面孔时，对照组梭状回的激活增加，而精神病组梭状回的激活减少。结论精神病患者与对照组在处理面部情绪时存在生理差异，不同情绪类型的反应模式也不同。利益声明无。
Background It has been suggested that people with psychopathic disorders lack empathy because they have deficits in processing distress cues (e.g. fearful facial expressions).Aims To investigate brain function when individuals with psychopathy and a control group process facial emotion.Method Using event-related functional magnetic resonance imaging we compared six people scoring >= 25 on the Hare Psychopathy Checklist-Revised and nine non-psychopathic healthy volunteers during an implicit emotion processing task using fearful, happy and neutral faces.Results The psychopathy group showed significantly less activation than the control group in fusiform and extrastriate cortices when processing both facial emotions. However, emotion type affected response pattern. Both groups increased fusiform and extrastriate cortex activation when processing happy faces compared with neutral faces, but this increase was significantly smaller in the psychopathy group. In contrast, when processing fearful faces compared with neutral faces, the control group showed increased activation but the psychopathy group decreased activation in the fusiform gyrus.Conclusions People with psychopathy have biological differences from controls when processing facial emotion, and the pattern of response differs according to emotion type. . Declaration of interest None.