Management of adrenocortical carcinoma: a consensus statement of the Italian Society of Endocrinology (SIE)
Management of adrenocortical carcinoma: a consensus statement of the Italian Society of Endocrinology (SIE)
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DOI：
10.1007/s40618-015-0349-9
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发表时间：
2016-01-01
影响因子：
5.4
通讯作者：
Terzolo, M.
中科院分区：
文献类型：
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作者：
Stigliano, A.;Chiodini, I.;Terzolo, M.
已接受：2015年6月23日/在线发布时间：2015年7月14日©意大利内分泌学会（SIE）2015年先进的ACC仍然令人失望的有限疗效和显着的毒性[1-3]。ACC的管理对医生和患者都具有挑战性，并且是临床内分泌学家最苛刻的任务之一。然而，内分泌学家应该参与ACC患者的管理，因为这种疾病及其治疗会导致内分泌系统的严重紊乱，对患者有害，并对预后产生负面影响。此外，内分泌科医生在诊断过程中发挥着独特的作用，由于患者没有被转诊给具有特定专业知识的医生，诊断过程往往被延误。因此，通常与乳腺癌有关的症状仍然被忽视。基于这些考虑，意大利内分泌学会（SIE）任命了一个肾上腺疾病领域的意大利专家小组，其任务是编写一份立场声明，其目的是审查和综合目前可用的关于ACC的证据，并提供
Accepted: 23 June 2015/Published online: 14 July 2015© Italian Society of Endocrinology (SIE) 2015 advanced ACC remains disappointing for limited efficacy and significant toxicity [1–3]. Management of ACC is challenging for both physicians and their patients and represents one of the most demanding tasks for clinical endocrinologists. However, endocrinologists should be involved in the management of patients with ACC because the disease and its treatment cause a profound derangement of the endocrine system that is harmful for patients and has a negative impact on prognosis. Moreover, endocrinologists play a unique role in the diagnostic process that is too often delayed because patients are not referred to physicians with specific expertise. Thus, presenting symptoms, that are often hormone-related, remain overlooked. On the basis of these considerations, the Italian Society of Endocrinology (SIE) appointed a panel of Italian experts in the field of adrenal diseases with the task to write a Position Statement whose intent was to review and synthesize currently available evidence regarding ACC and provide