Roles of oxidative stress in stomach disorders.
Roles of oxidative stress in stomach disorders.
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DOI：
10.3164/jcbn.11-115sr
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发表时间：
2012-01
影响因子：
2.4
通讯作者：
Hibi T
中科院分区：
文献类型：
--
作者：
Suzuki H;Nishizawa T;Tsugawa H;Mogami S;Hibi T
胃是一个敏感的消化器官，容易受到并暴露于饮食中的外源性病原体。在对这些病原体的反应中，胃诱导氧化应激，这可能与胃器质性疾病如胃炎、胃溃疡和胃癌以及功能性疾病如功能性消化不良的发展有关。特别是，幽门螺杆菌在引发和对抗胃中的氧化应激方面起着重要作用。本文就氧化应激在各种胃病发生发展过程中的作用机制作一综述。
The stomach is a sensitive digestive organ that is susceptible and exposed to exogenous pathogens from the diet. In response to such pathogens, the stomach induces oxidative stress, which might be related to the development of gastric organic disorders such as gastritis, gastric ulcers, and gastric cancer, as well as functional disorders such as functional dyspepsia. In particular, the bacterium Helicobacter pylori plays a major role in eliciting and confronting oxidative stress in the stomach. The present paper summarizes the pathogenesis of oxidative stress in the stomach during the development of various stomach diseases.