Computing health quality measures using Informatics for Integrating Biology and the Bedside.
Computing health quality measures using Informatics for Integrating Biology and the Bedside.
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DOI：
10.2196/jmir.2493
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发表时间：
2013-04-19
影响因子：
7.4
通讯作者：
Murphy SN
中科院分区：
文献类型：
--
作者：
Klann JG;Murphy SN
健康质量衡量标准 (HQMF) 是一种健康级别 7 (HL7) 标准，用于表达可计算的临床质量衡量标准 (CQM)。随着美国将其健康信息技术战略计划推进到有意义使用激励计划（MU2 和 MU3）的第 2 和第 3 阶段，创建用于处理临床数据库中的 HQMF 查询的工具将变得越来越重要。整合生物学和床边信息学 (i2b2) 是分析数据库之一，用作国家协调员办公室 (ONC) 查询健康平台的一部分，以实现这一目标。我们的目标是将 i2b2 与 Query Health HQMF 架构集成，为其他 HQMF 用例（例如 MU2 和 MU3）做好准备，并阐明 i2b2 和 HQMF 之间的功能重叠。因此，我们分析了HQMF的结构，然后将这种理解应用于i2b2临床分析数据库平台上的HQMF计算。具体来说，我们开发了 HQMF 和 i2b2 两种查询语言之间的翻译器，以便 i2b2 平台可以计算 HQMF 查询。我们使用 HQMF 查询结构进行聚合报告，它定义临床数据元素以及它们之间的时间和逻辑关系。我们使用 i2b2 XML 格式，它允许以易于理解的特定领域语言灵活查询复杂的临床数据存储库。翻译器可以将几乎任何 i2b2-XML 查询表示为 HQMF，并在 i2b2 中执行几乎任何可以用 i2b2-XML 表示的 HQMF 查询。该转换器是 QueryHealth 计划免费参考实现的一部分。我们分析了转换的局限性，发现它涵盖了质量度量所需的许多（但不是全部）复杂的时间和逻辑运算符。 HQMF 是一种用于定义质量度量的表达语言，无论是在有意义的使用还是人口健康方面，理解和实施 CQM 计算都非常重要。然而，它当前的形式可能会带来当前数据库系统难以处理的复杂性（无论是在实现还是计算方面）。我们的翻译器支持当前以 i2b2-XML 表示的 HQMF 子集，这可能代表了实际妥协的开始。它正在两个 Query Health 演示项目中进行试点测试，并且可以进一步扩展以平衡计算可处理性与度量开发人员所需的高级功能。
The Health Quality Measures Format (HQMF) is a Health Level 7 (HL7) standard for expressing computable Clinical Quality Measures (CQMs). Creating tools to process HQMF queries in clinical databases will become increasingly important as the United States moves forward with its Health Information Technology Strategic Plan to Stages 2 and 3 of the Meaningful Use incentive program (MU2 and MU3). Informatics for Integrating Biology and the Bedside (i2b2) is one of the analytical databases used as part of the Office of the National Coordinator (ONC)’s Query Health platform to move toward this goal. Our goal is to integrate i2b2 with the Query Health HQMF architecture, to prepare for other HQMF use-cases (such as MU2 and MU3), and to articulate the functional overlap between i2b2 and HQMF. Therefore, we analyze the structure of HQMF, and then we apply this understanding to HQMF computation on the i2b2 clinical analytical database platform. Specifically, we develop a translator between two query languages, HQMF and i2b2, so that the i2b2 platform can compute HQMF queries. We use the HQMF structure of queries for aggregate reporting, which define clinical data elements and the temporal and logical relationships between them. We use the i2b2 XML format, which allows flexible querying of a complex clinical data repository in an easy-to-understand domain-specific language. The translator can represent nearly any i2b2-XML query as HQMF and execute in i2b2 nearly any HQMF query expressible in i2b2-XML. This translator is part of the freely available reference implementation of the QueryHealth initiative. We analyze limitations of the conversion and find it covers many, but not all, of the complex temporal and logical operators required by quality measures. HQMF is an expressive language for defining quality measures, and it will be important to understand and implement for CQM computation, in both meaningful use and population health. However, its current form might allow complexity that is intractable for current database systems (both in terms of implementation and computation). Our translator, which supports the subset of HQMF currently expressible in i2b2-XML, may represent the beginnings of a practical compromise. It is being pilot-tested in two Query Health demonstration projects, and it can be further expanded to balance computational tractability with the advanced features needed by measure developers.
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影响因子：
--
作者：
Marcotte, Leah;Seidman, Joshua;Jain, Sachin H.
通讯作者：
Jain, Sachin H.
DOI：
10.1136/jamia.2009.000893
发表时间：
2010-03-01
影响因子：
6.4
作者：
Murphy, Shawn N.;Weber, Griffin;Kohane, Isaac
通讯作者：
Kohane, Isaac
为哮喘研究提取主要诊断、并发症和吸烟状况：对自然语言处理系统的评估。
影响因子：
3.5
作者：
Zeng, Qing T;Goryachev, Sergey;Lazarus, Ross
通讯作者：
Lazarus, Ross
影响因子：
9.7
作者：
Diamond, Carol C.;Mostashari, Farzad;Shirky, Clay
通讯作者：
Shirky, Clay
DOI：
10.1197/jamia.m3191
发表时间：
2009-09-01
影响因子：
6.4
作者：
Weber, Griffin M.;Murphy, Shawn N.;Kohane, Isaac S.
通讯作者：
Kohane, Isaac S.