Effect of Collimator Selection on Tumor Detection for Dedicated Nuclear Breast Imaging Systems
Effect of Collimator Selection on Tumor Detection for Dedicated Nuclear Breast Imaging Systems
复制标题
准直器选择对专用核乳腺成像系统肿瘤检测的影响
DOI：
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发表时间：
2006
影响因子：
1.8
通讯作者：
M. O’Connor
中科院分区：
文献类型：
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作者：
C. Hruska;M. O’Connor
确定了准直对使用专用核乳腺成像系统检测微小(1厘米)乳腺肿瘤的影响。使用三个专用系统(GE Medical Prototype CZT、Gamma Medica LumaGEM 3200 S和Digirad 2020 TC)和常规伽马相机(Elscint Helix)，使用从LEUHS到LEUHR的各种系统特定和通用准直器对直径4-9 mm的乳腺模型进行成像。采集使用从患者检查分析中确定的临床相关计数密度。肿瘤位于距准直器1 cm、3 cm和5 cm处，肿瘤与背景的比例从3：1到35：1不等。测量每幅图像的肿瘤信噪比(SNR)。SNR测量表明，通用或高灵敏度的准直器是检测靠近准直器表面的小肿瘤的最佳选择。这三个像素化系统给出了相似的结果，而且表现明显好于传统的伽马相机。
The effect of collimation on the detection of small (<1 cm) breast tumors with dedicated nuclear breast imaging systems was determined. A breast phantom modeling tumors 4-9 mm in diameter was imaged with three dedicated systems (GE Medical Prototype CZT, Gamma Medica LumaGEM 3200 s, and Digirad 2020 tc), and a conventional gamma camera (Elscint Helix) using a variety of system-specific and generic collimators ranging from LEUHS to LEUHR. Acquisitions were performed using clinically relevant count densities determined from analysis of patient exams. Tumors were placed at depths of 1, 3, and 5 cm from the collimator in a 6-cm-thick breast, and tumor-to-background ratio was varied from 3:1 to 35:1. Tumor signal-to-noise ratio (SNR) was measured in each image. SNR measurements showed that an all-purpose or high sensitivity collimator is optimal for the detection of small tumors close to the collimator face. The three pixilated systems gave similar results and performed significantly better than the conventional gamma camera