Mandibular Tissue Engineering: Past, Present, Future
Mandibular Tissue Engineering: Past, Present, Future
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DOI：
10.1016/j.joms.2015.05.037
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发表时间：
2015-12-01
影响因子：
1.9
通讯作者：
Troulis, Maria J.
中科院分区：
文献类型：
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作者：
Konopnicki, Sandra;Troulis, Maria J.
近20年前，资深作者(M.T.J.)第一篇文章是与我们的导师伦纳德·B·卡班博士一起撰写的，一篇题为《分心成骨：过去、现在和未来》的评论文章。1998年，许多人认为不可能有一个远程激活的、小的、曲线形的牵引器，可以使用内窥镜技术放置。目前，用于颌骨重建的微创入路的曲线自动化装置和内窥镜技术已在美国获得专利。随着颌骨重建的微创进入，降低供区发病率的负担增加了。牵张成骨(DO)是一种活体组织工程形式。DO技术不需要供体部位，侵入性更小，手术时间比通常的手术更短，可以用于多种重建应用。组织工程可以进一步降低发病率和成本，增加治疗的可得性。本报告的目的是回顾我们在骨组织工程方面的经验：过去、现在和我们对未来的展望。本报告向我们的导师致敬，并感谢卡班博士不断的指导、指导、智慧和无限的远见。(C)2015年美国口腔颌面外科医生协会
Almost 2 decades ago, the senior author's (M.T.J.) first article was with our mentor, Dr Leonard B. Kaban, a review article titled "Distraction Osteogenesis: Past, Present, Future." In 1998, many thought it would be impossible to have a remotely activated, small, curvilinear distractor that could be placed using endoscopic techniques. Currently, a U.S. patent for a curvilinear automated device and endoscopic techniques for minimally invasive access for jaw reconstruction exist. With minimally invasive access for jaw reconstruction, the burden to decrease donor site morbidity has increased. Distraction osteogenesis (DO) is an in vivo form of tissue engineering. The DO technique eliminates a donor site, is less invasive, requires a shorter operative time than usual procedures, and can be used for multiple reconstruction applications. Tissue engineering could further reduce morbidity and cost and increase treatment availability. The purpose of the present report was to review our experience with tissue engineering of bone: the past, present, and our vision for the future. The present report serves as a tribute to our mentor and acknowledges Dr Kaban for his incessant tutelage, guidance, wisdom, and boundless vision. (C) 2015 American Association of Oral and Maxillofacial Surgeons