Prevalence, incidence, morbidity and treatment patterns in a cohort of patients diagnosed with anxiety in UK primary care
Prevalence, incidence, morbidity and treatment patterns in a cohort of patients diagnosed with anxiety in UK primary care
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DOI：
10.1093/fampra/cmp071
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发表时间：
2010-02-01
期刊：
影响因子：
2.2
通讯作者：
Alberto Garcia-Rodriguez, Luis
中科院分区：
文献类型：
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作者：
Martin-Merino, Elisa;Ruigomez, Ana;Alberto Garcia-Rodriguez, Luis
背景焦虑症是常见的，可导致生活质量的实质性损害。本研究的目的是调查英国初级保健中焦虑的频率。治疗模式和焦虑诊断相关的因素也进行了评估。健康改善网络被用来确定所有患者年龄在10-79岁，在2002-04年新诊断的焦虑（n = 40 873）和年龄，性别和年龄匹配的对照组（n = 50 000）。采用巢式病例对照分析，通过多因素Logistic回归分析焦虑的潜在危险因素。焦虑的患病率为7.2%，发病率为9.7/1000人年。妇女和年轻人（20-29岁）的发病率和流行率最高。焦虑与酗酒、吸烟和成瘾问题以及压力、睡眠和抑郁症有关。焦虑症患者比对照组更频繁地使用医疗服务。在被诊断为焦虑的患者中，63%的人接受了治疗。抗抑郁药占处方的近80%。焦虑的患病率和发病率在英国初级保健中很高，女性几乎是男性的两倍。焦虑与其他精神病发病率以及频繁使用医疗保健有关。抗抑郁药是最常用的药物治疗。
Background. Anxiety disorders are common and can cause substantial quality of life impairment.Objective. The aim of this study was to investigate the frequency of anxiety in UK primary care. Treatment patterns and factors associated with an anxiety diagnosis were also assessed.Methods. The Health Improvement Network was used to identify all patients aged 10-79 years with a new diagnosis of anxiety in 2002-04 (n = 40 873) and age-, sex- and calendar-year-matched controls (n = 50 000). A nested case-control analysis was used to quantify potential risk factors for anxiety by multivariate logistic regression.Results. The prevalence of anxiety was 7.2% and the incidence was 9.7 per 1000 person-years. Incidence and prevalence were highest in women and young adults (20-29 years). Anxiety was associated with heavy alcohol use, smoking and addiction problems as well as stress, sleep and depression disorders. Anxiety patients used health care services more frequently than controls. Among patients diagnosed with anxiety, 63% were treated pharmacologically. Antidepressants accounted for almost 80% of prescriptions.Conclusions. The prevalence and incidence of anxiety are high in UK primary care and are almost twice as high in women than in men. Anxiety is associated with other psychiatric morbidity as well as frequent health care use. Antidepressants are the most commonly used pharmacological treatment.