Autograft Reinforcement to Preserve Autograft Function After the Ross Procedure A Report From the German-Dutch Ross Registry
Autograft Reinforcement to Preserve Autograft Function After the Ross Procedure A Report From the German-Dutch Ross Registry
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DOI：
10.1161/circulationaha.108.843391
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发表时间：
2009-09-15
期刊：
影响因子：
37.8
通讯作者：
Sievers, Hans H.
中科院分区：
文献类型：
--
作者：
Charitos, Efstratios I.;Hanke, Thorsten;Sievers, Hans H.
背景-Ross手术期间自体移植物加固干预（R）旨在保留自体移植物功能并提高耐久性。本研究的目的是评估这一hypothes.Methods和结果-1335例成人患者（平均年龄：43.5 +/- 12.0岁）进行了罗斯程序（冠状动脉下，SC，n=637;根置换，根，n=698）。592例患者接受了瓣环、窦管交界处或两者的R。定期进行临床和超声心动图随访（平均值：6.09 ± 3.97，范围：0.01 - 19.2年）。采用多级模型技术对自体移植物功能随时间的变化进行纵向评估。与Root with R（Root+R）、SC with R（SC+R）和无R（SC-R; 12.9% vs 2.3% vs 2.5%）相比，Root without R（Root-R）组的再手术率增加6倍。分别为2.6%和2.6%; P
Background-Autograft reinforcement interventions (R) during the Ross procedure are intended to preserve autograft function and improve durability. The aim of this study is to evaluate this hypothesis.Methods and Results-1335 adult patients (mean age: 43.5 +/- 12.0 years) underwent a Ross procedure (subcoronary, SC, n=637; root replacement, Root, n=698). 592 patients received R of the annulus, sinotubular junction, or both. Regular clinical and echocardiographic follow-up was performed (mean: 6.09 +/- 3.97, range: 0.01 to 19.2 years). Longitudinal assessment of autograft function with time was performed using multilevel modeling techniques. The Root without R (Root-R) group was associated with a 6x increased reoperation rate compared to Root with R (Root+R), SC with R (SC+R), and without R (SC-R; 12.9% versus 2.3% versus 2.5%. versus 2.6%, respectively; P