Comparison of swept-source and enhanced depth imaging spectral-domain optical coherence tomography in quantitative characterisation of the optic nerve head
Comparison of swept-source and enhanced depth imaging spectral-domain optical coherence tomography in quantitative characterisation of the optic nerve head
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DOI：
10.1136/bjophthalmol-2016-308586
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发表时间：
2017-03-01
影响因子：
4.1
通讯作者：
Shen, Lucy Q.
中科院分区：
文献类型：
--
作者：
Li, Dejiao;Taniguchi, Elise V.;Shen, Lucy Q.
目的比较扫频光源光学相干断层扫描（SS-OCT）和增强深度成像光谱域OCT（EDI-OCT）在定量评估视神经乳头（ONH）parameters.Methods在一项横断面研究中，原发性开角型青光眼（POAG）患者和年龄匹配的对照组进行SS-OCT和EDI-OCT的ONH B扫描在一次访问。两名蒙眼阅片员独立测量了水平和垂直筛板深度（分别为LCDH和LCDV），以及SS-OCT和EDI-OCT扫描的最薄Bruch膜开口最小边缘宽度（BMO-MRW）。我们通过线性回归模型、Bland-Altman分析和一致性相关系数（CCC）评估了SS-OCT和EDI-OCT测量之间的一致性。采用组内相关系数（ICC）评估阅片者内和阅片者间的重复性。SS-OCT的所有三个ONH测量值均高于EDI-OCT，LCDH存在显著差异（每个参数的平均差异=31.7 μ m，总体p <0.8）。Intrareader和interreader ICC分别为0.989和0.964，所有parameters.Conclusions LCDH，LCDV和最薄的BMO-MRW测量之间的SS-OCT和EDI-OCT是不可互换的，但显示良好的intrareader和interreproducibility和interdevice agreement定量表征的ONH，特别是青光眼患者。
Aims To compare swept-source optical coherence tomography (SS-OCT) and enhanced depth imaging spectral-domain OCT (EDI-OCT) in quantitative assessment of optic nerve head (ONH) parameters.Methods In a cross-sectional study, patients with primary open angle glaucoma (POAG) and age-matched control subjects underwent SS-OCT and EDI-OCT B-scans of the ONH in a single visit. Two masked readers independently measured the horizontal and vertical lamina cribrosa depth (LCDH and LCDV, respectively), as well as thinnest Bruch's membrane opening minimum rim width (BMO-MRW) from SS-OCT and EDI-OCT scans. We assessed agreement between SS-OCT and EDI-OCT measurements by linear regression models, Bland-Altman analysis and concordance correlation coefficients (CCC). Intrareader and inter-reader reproducibility was assessed using intraclass correlation coefficients (ICC).Results One eye from each of 40 patients with POAG and 20 controls were included. All three ONH measurements were higher on SS-OCT than on EDI-OCT, with significant differences in LCDH (mean difference=31.7 mu m, p0.8 overall for each parameter. Intrareader and inter-reader ICCs were 0.989 and 0.964, respectively, for all parameters.Conclusions LCDH, LCDV and thinnest BMO-MRW measurements are not interchangeable between SS-OCT and EDI-OCT, but show good intrareader and inter-reader reproducibility and interdevice agreement for quantitative characterisation of the ONH, particularly among patients with glaucoma.