The National Institutes of Allergy and Infectious Diseases networks on asthma in inner-city children: An approach to improved care
The National Institutes of Allergy and Infectious Diseases networks on asthma in inner-city children: An approach to improved care
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DOI：
10.1016/j.jaci.2010.01.036
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发表时间：
2010-03-01
影响因子：
14.2
通讯作者：
Busse, William W.
中科院分区：
文献类型：
--
作者：
Busse, William W.
哮喘在市中心儿童中很普遍，严重程度增加，对许多患者来说难以控制。虽然城市儿童哮喘控制的一些限制包括社会经济负担，但其他因素，如环境过敏原，污染物，感染和压力，对这些儿童的疾病负担有显着影响。由于市中心儿童哮喘控制的这些未满足的需求，国家过敏和传染病研究所建立了研究网络，最终目标是改善对这一高危人群的护理。内城哮喘网络计划始于1991年，在随后的几年里，资助了3个不同的网络，这些网络有一个共同的目标：改善对哮喘儿童的护理。这些网络中的每一个都扩大了我们对市中心哮喘和哮喘的一般知识。国家过敏和传染病研究所的努力继续与目前的内城网络，内城哮喘联盟2。下面的文章将讨论这些内城网络在哮喘研究中的应用，每个网络的贡献，以及内城哮喘联盟2下新提出的努力如何提高我们对内城儿童哮喘的理解和最终控制。（J Allergy Clin Immunol 2010;125：529-37.）
Asthma in inner-city children is prevalent, has increased severity, and for many patients poses difficulty in achieving control. Although some of the limitations to asthma control in inner-city children include socioeconomic burdens, other factors, such as environmental allergens, pollutants, infections, and stress, contribute significantly to the disease burden found in these children. As a consequence of these unmet needs for asthma control in inner-city children, the National Institute of Allergy and Infectious Diseases established research networks with an ultimate goal of improving care for this at-risk population. The Inner-City Asthma Network Program began in 1991 and has, over the ensuing years, funded 3 distinct networks that have a common goal: to improve care for the child with asthma. Each of these networks has expanded our knowledge about asthma in the inner cities and asthma in general. The National Institute of Allergy and Infectious Diseases' efforts continue with the current inner-city network, the Inner City Asthma Consortium 2. The following article will discuss the application of these inner-city networks to the study of asthma, the contributions of each of the individual networks, and how newly proposed efforts under the Inner City Asthma Consortium 2 propose to improve our understanding and eventual control of asthma in inner-city children. (J Allergy Clin Immunol 2010;125:529-37.)