Respiratory motion artefacts in dynamic liver MRI: a comparison using gadoxetate disodium and gadobutrol
Respiratory motion artefacts in dynamic liver MRI: a comparison using gadoxetate disodium and gadobutrol
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DOI：
10.1007/s00330-015-3736-x
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发表时间：
2015-11-01
影响因子：
5.9
通讯作者：
Kukuk, Guido M.
中科院分区：
文献类型：
--
作者：
Luetkens, Julian A.;Kupczyk, Patrick A.;Kukuk, Guido M.
我们的目的是回顾性地评价使用钆塞酸二钠或钆布醇进行动态肝脏磁共振（MR）的患者中呼吸运动伪影的发生率，分析了230例肝脏MR研究（115例使用钆布醇，115例使用钆塞酸二钠）。使用五点评定量表评估动态3D T1加权MR图像（造影前、动脉、静脉和动态晚期）上的呼吸运动伪影。严重运动被定义为每千日元4欧元的分数。采用Mann-Whitney-U检验比较平均运动评分。卡方检验用于二分类比较，钆塞酸二钠和钆布醇的平均运动评分在动态对比系列的每个阶段没有相关差异（造影前：1.85 +/- 0.70 vs. 1.88 +/- 0.57，动脉：1.85 +/- 0.81 vs. 1.87 +/- 0.74，静脉：1.82 +/- 0.67 vs. 1.74 +/- 0.64，晚期动态：1.75 +/- 0.62 vs. 1.79 +/- 0.63; p分别= 0.469、0.557、0.382和0.843）。使用钆塞酸二钠和钆布醇时，严重运动伪影的发生率相似（11/460 [2.4%] vs. 7/460 [1.5%]; p = 0.341）。在动态肝脏MRI中，钆塞酸二钠与钆布醇的运动评分相当。此外，两种造影剂的严重呼吸运动伪影发生率相当且可接受。a在动态相位成像中，钆布醇和钆塞酸二钠的运动评分相当。a在动脉相位成像中，严重运动伪影的发生率明显。a在使用钆塞酸二钠的115次检查中，未记录到不良呼吸副作用。
Our aim was to retrospectively evaluate the occurrence of respiratory motion artefacts in patients undergoing dynamic liver magnetic resonance (MR) either with gadoxetate disodium or gadobutrol.Two hundred and thirty liver MR studies (115 with gadobutrol, 115 with gadoxetate disodium) were analysed. Respiratory motion artefacts on dynamic 3D T1-weighted MR images (pre-contrast, arterial, venous, and late-dynamic phase) were assessed using a five-point rating scale. Severe motion was defined as a score a parts per thousand yenaEuro parts per thousand 4. Mean motion scores were compared with the Mann-Whitney-U-test. The chi-squared-test was used for dichotomous comparisons.Mean motion scores for gadoxetate disodium and gadobutrol showed no relevant differences for each phase of the dynamic contrast series (pre-contrast: 1.85 +/- 0.70 vs. 1.88 +/- 0.57, arterial: 1.85 +/- 0.81 vs. 1.87 +/- 0.74, venous: 1.82 +/- 0.67 vs. 1.74 +/- 0.64, late-dynamic: 1.75 +/- 0.62 vs. 1.79 +/- 0.63; p = 0.469, 0.557, 0.382 and 0.843, respectively). Severe motion artefacts had a similar incidence using gadoxetate disodium and gadobutrol (11/460 [2.4 %] vs. 7/460 [1.5 %]; p = 0.341).Gadoxetate disodium is associated with equivalent motion scores compared to gadobutrol in dynamic liver MRI. In addition, both contrast agents demonstrated a comparable and acceptable rate of severe respiratory motion artefacts.aEuro cent Gadobutrol and gadoxetate disodium showed comparable motion scores in dynamic phase imaging.aEuro cent The incidence of severe motion artefacts was pronounced in arterial phase imaging.aEuro cent Adverse respiratory side effects were not recorded in 115 examinations with gadoxetate disodium.