Does Pneumocystis carinii prophylaxis still need to be lifelong?
Does Pneumocystis carinii prophylaxis still need to be lifelong?
复制标题
卡氏肺孢子虫预防仍需终生吗？
DOI：
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发表时间：
1999
影响因子：
158.5
通讯作者：
J. Kaplan
中科院分区：
文献类型：
--
作者：
H. Masur;J. Kaplan
在抗逆转录病毒治疗和预防卡氏肺孢子虫肺炎出现之前，北美和西欧 60% 至 80% 的人类免疫缺陷病毒 (HIV) 感染成年患者最终出现这种类型的肺炎。1 70% 的患者在第一次发作后 12 个月内发生第二次卡氏肺孢子虫肺炎。1 实施预防措施以防止肺炎初次发作（一级预防）或后续发作（二级预防）是第一个显着提高 HIV 感染患者生存率并改善生活质量的干预措施。随后人们认识到。 。 。
Before the advent of antiretroviral therapy and prophylaxis against Pneumocystis carinii pneumonia, this type of pneumonia ultimately developed in 60 to 80 percent of adult patients with human immunodeficiency virus (HIV) infection in North America and Western Europe.1 Seventy percent of patients had a second episode of P. carinii pneumonia within 12 months after the first episode.1 The implementation of prophylaxis to prevent an initial episode of pneumonia (primary prophylaxis) or a subsequent episode (secondary prophylaxis) was the first intervention that substantially increased survival and improved the quality of life for patients with HIV infection. It was subsequently recognized that . . .
影响因子：
158.5
作者：
PHAIR, J;MUNOZ, A;SAAH, A
通讯作者：
SAAH, A