SPREAD OF SEIZURE DISCHARGES IN EPILEPSY - ANATOMICAL AND ELECTROPHYSIOLOGICAL CONSIDERATIONS
SPREAD OF SEIZURE DISCHARGES IN EPILEPSY - ANATOMICAL AND ELECTROPHYSIOLOGICAL CONSIDERATIONS
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DOI：
10.1016/0014-4886(72)90022-2
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发表时间：
1972-01-01
影响因子：
5.3
通讯作者：
BRAZIER, MAB
中科院分区：
文献类型：
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作者：
BRAZIER, MAB
为了追踪癫痫患者脑内自发电发作活动的传播，人们利用这个机会跟踪了癫痫患者中这些发作的发生和时间发展，这些患者为了诊断、定侧和后来的治疗手术而放置了留置电极。一个计算机程序被用来检测每一次无端的异常波列爆发的基本频率，并跟踪它们从启动驱动区到通过这种传播到达的大脑其他部分。自发癫痫活动扩散到其他结构所遵循的路径是每个人特有的特征，可以通过这种方法为该患者建立。提到了提供一种比颞叶切除术更受限的治疗手术的可能性。
In an attempt to trace the spread of spontaneous electrical seizure activity within the brain of epileptics, the opportunity has been taken to follow the occurrence and temporal development of these outbursts in patients with epilepsy who have had indwelling electrodes placed for purposes of diagnosis, lateralization and later therapeutic surgery. A computer program has been used to detect the essential frequency or frequencies in each unprovoked burst of abnormal wavetrains and to follow their passage from the initiating driving zone to the other parts of the brain that are reached by this spread. The path followed by spontaneous seizure activity in spreading to other structures is a feature peculiar to each individual and can be established for that patient by this method. The possibility offered for a type of therapeutic surgery more restricted than temporal lobectomy is mentioned.