New International Association of the Diabetes and Pregnancy Study Groups (IADPSG) recommendations for diagnosing gestational diabetes compared with former criteria: a retrospective study on pregnancy outcome
New International Association of the Diabetes and Pregnancy Study Groups (IADPSG) recommendations for diagnosing gestational diabetes compared with former criteria: a retrospective study on pregnancy outcome
复制标题
DOI：
10.1111/j.1464-5491.2011.03351.x
复制
发表时间：
2011-09-01
影响因子：
3.5
通讯作者：
Fedele, D.
中科院分区：
文献类型：
--
作者：
Lapolla, A.;Dalfra, M. G.;Fedele, D.
目的国际糖尿病与妊娠研究组协会（IADPSG）共识小组建议诊断妊娠糖尿病的新标准。我们评估的临床和代谢特征，妊娠结局，妇女先前被归类为“正常”根据第四届国际研讨会会议妊娠期糖尿病标准，但重新归类为“异常”根据新的recommendations.Methods使用新的IADPSG标准，3953例妊娠被回顾性重新分类为1815例糖耐量正常的妇女和2138例妊娠糖尿病，112结果在2138例按新标准诊断为异常的妇女中，现在被重新归类为异常的112名妇女更年轻，怀孕BMI比2026名妇女谁也被归类为异常之前的标准。100克口服葡萄糖耐量试验显示，这112名妇女的葡萄糖水平明显高于1815名重新归类为正常的妇女（P < 0.0001）。剖腹产的频率明显更高新生儿体重指数明显高于正常组（P < 0.01）（P < 0.0001），基础血糖水平与体重指数显著相关（P < 0.05）。结论新的妊娠期糖尿病诊断标准确定了一组以前根据第四届国际糖尿病诊断标准被归类为正常的妇女。研讨会的标准，但揭示代谢特征和妊娠结局类似的妇女谁会被认为是有妊娠糖尿病的以前的标准。
Aims The International Association of the Diabetes and Pregnancy Study Groups (IADPSG) Consensus Panel recommends new criteria for diagnosing gestational diabetes. We evaluated the clinical and metabolic characteristics, and pregnancy outcome, in women previously classifiable as 'normal' according to the 4th International Workshop Conference on gestational diabetes criteria, but reclassified as 'abnormal' according to the new recommendations.Methods Using the new IADPSG criteria, 3953 pregnancies were retrospectively reclassified as 1815 women with normal glucose tolerance and 2138 with gestational diabetes, 112 (2.8%) of whom would have been classified as normal according to the older criteria.Results Of the 2138 women classified as abnormal by the new criteria, the 112 women now reclassified as abnormal were younger and had a lower pre-pregnancy BMI than the 2026 women who had also been classified as abnormal by the previous criteria. The 100-g oral glucose tolerance test showed significantly higher glucose levels in these 112 women than in the 1815 women reclassified as normal (P < 0.0001). Caesarean section was significantly more frequent (P < 0.01) and the ponderal index for the newborn significantly higher in these reclassified women than in those classified as normal (P < 0.0001), and their basal glucose levels correlated significantly with the ponderal index (P < 0.05).Conclusion The new criteria for diagnosing gestational diabetes identified a group of women previously classifiable as normal according to the 4th International Workshop Conference criteria, but revealing metabolic characteristics and pregnancy outcomes resembling those of women who would have been considered to have gestational diabetes by the previous criteria.