Effect of load variation on the friction properties of articular cartilage
Effect of load variation on the friction properties of articular cartilage
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DOI：
10.1243/13506501jet240
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发表时间：
2007-05-01
影响因子：
2
通讯作者：
Fisher, J.
中科院分区：
文献类型：
--
作者：
Katta, J.;Pawaskar, S. S.;Fisher, J.
滑膜关节以其卓越的承载能力而闻名，同时在其寿命期间保持非常低的摩擦和磨损。虽然其他关节成分在润滑机制中发挥作用，但具有独特双相特征的关节软骨被认为是这些关节中观察到的低摩擦特性的主要原因。在本研究中，使用钉-板机在软骨对软骨配置加载，以研究载荷变化对软骨摩擦性能的影响。在三种不同的接触应力水平（0.2、0.3和0.4 MPa）下，使用磷酸盐缓冲盐水作为润滑剂，对静态和动态载荷条件进行了测试。压痕实验进行和建模，通过有限元（FE）方法，以确定双相材料特性的软骨。然后使用采用软骨的衍生双相特性的第二个FE模型来模拟静摩擦测试，并确定在不同载荷下软骨组织中的间质液载荷支撑。在动态和静态模型中，发现接触应力的增加显著降低了关节软骨表面之间的摩擦水平（p < 0.05），而软骨内的流体负载支撑百分比几乎相同。结果表明，虽然软骨的间质液加压起主要作用，但需要另一种影响软骨表面之间摩擦的外来因素或机制来完全解释观察到的结果。
Synovial joints are known for their remarkable load bearing capacity while maintaining very low friction and wear over their lifetime. Although other joint components play a role in the lubrication mechanisms, articular cartilage with its unique biphasic characteristics is believed to be largely responsible for the observed low friction properties in these joints. In the current study, a pin-on-plate machine was used in a cartilage loaded against cartilage configuration to study the effect of load variation on cartilage friction properties. Both static and dynamic loading conditions were tested under three different contact stress levels - 0.2, 0.3, and 0.4 MPa with phosphate buffered saline as the lubricant. Indentation experiments were performed and modelled through finite-element (FE) method to determine the biphasic material properties of cartilage. A second FE model adopting the derived biphasic properties of cartilage was then used to simulate the static friction tests and determine the interstitial fluid load support in the cartilage tissue under different loads. An increase in contact stress was found to reduce the friction levels significantly (p < 0.05) between the articulating cartilage surfaces in both dynamic and static models, while the percentage of fluid load support within the cartilage was almost identical. It was shown that while interstitial fluid pressurization of cartilage plays the major role, another extraneous factor or mechanism that influences the friction between cartilage surfaces is needed to completely explain the results observed.