Stromal microsporidial keratitis successfully treated with medical therapy.
Stromal microsporidial keratitis successfully treated with medical therapy.
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基质微孢子虫性角膜炎成功治疗药物治疗。
DOI：
10.1016/j.ajoc.2021.101178
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发表时间：
2021-09
影响因子：
--
通讯作者：
Espana EM
中科院分区：
文献类型：
--
作者：
Donovan CP;Margo CE;Espana EM
报告一位以口服阿苯达唑及外用伏立康唑成功治疗严重基质型小孢子菌性角膜炎的病例。一位71岁男性，因进行性视力下降及角膜混浊一年来就诊。最初的视力是数手指归因于一个致密的上皮下混浊。共聚焦显微镜检查和随后的角膜活检导致微孢子虫性角膜炎的诊断。患者完成了为期四周的口服阿苯达唑和局部伏立康唑疗程，导致角膜混浊消退，视力改善至20/250。口服阿苯达唑和外用伏立康唑4周疗程是治疗严重基质微孢子虫性角膜炎的有效方法。
To report a case of severe stromal microsporidal keratitis successfully treated with oral albendazole and topical voriconazole. A 71-year-old man presented with progressive vision loss and corneal opacification for one year. Initial visual acuity was counting fingers attributed to a dense subepithelial opacification. Confocal microscopy and subsequent corneal biopsy lead to the diagnosis of microsporidial keratitis. The patient completed a four-week course of oral albendazole and topical voriconazole which resulted in resolution of the corneal opacification and improvement in visual acuity to 20/250. A four-week course of oral albendazole and topical voriconazole was an effective treatment for severe stromal microsporidial keratitis.