Studies in Carcinogenesis. XVI. Production of Subcutaneous Tumors in Mice by Miscellaneous Polycyclic Compounds
Studies in Carcinogenesis. XVI. Production of Subcutaneous Tumors in Mice by Miscellaneous Polycyclic Compounds
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致癌作用研究。
DOI：
10.1093/jnci/2.3.241
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发表时间：
1941
期刊：
影响因子：
--
通讯作者：
J. Leiter
中科院分区：
文献类型：
--
作者：
M. J. Shear;J. Leiter
As regards direct injection into the spleen, Ilfeld (7), using Shear's (2) cholesterol-hydrocarbon technique, did not obtain any tumors of the spleen in 56 animals (50 mice and 6 rats) with pellets that contained 5 percent of 1, 2, 5, 6-dibenzanthracene 3; with pellets containing 5 percent of 20-methylcholanthrene 3 he obtained a sarcoma of the spleen in 1 mouse (2 animals injected; 1 mouse and 1 rat). Furth and Furth (3) obtained splenic sarcomas in 2 of 96 mice, of 5 different strains, with 0.05 cc. of a 4-percent solution of 3, 4-benzpyrene 3 in lard; the 2 cases of hemangioma of the liver and spleen which occurred in their mice were not definitely classified as induced or spontaneous. Rusch, Baumann,
