Differential roles of frequency-following and frequency-doubling visual responses revealed by evoked neural harmonics.
Differential roles of frequency-following and frequency-doubling visual responses revealed by evoked neural harmonics.
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DOI：
10.1162/jocn.2010.21536
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发表时间：
2011-08
影响因子：
3.2
通讯作者：
Suzuki S
中科院分区：
文献类型：
--
作者：
Kim YJ;Grabowecky M;Paller KA;Suzuki S
频率跟踪和倍频神经元在纹状体和纹外视区中普遍存在。然而，这两种类型的神经群体的反应在人类中还没有得到有效的比较，因为以前的脑电研究没有成功地将这些群体的反应分离出来。我们设计了一种明暗闪烁刺激，可以毫不含糊地区分这些反应，反映在稳态视觉诱发电位的第一和第二次谐波中。这些谐波揭示了频率跟随(一次谐波)和倍频(二次谐波)神经种群在空间和功能上的分离。在空间上，稳态视觉诱发电位的第一次和第二次谐波在广泛的脑电频率范围内显示出不同的头皮后部地形图。头皮最大值在一次谐波中位于内侧，而在二次谐波中处于对侧，这种差异与绝对反应频率无关。在功能上，随意的视觉空间注意强烈地调制了二次调和，但对同时引起的一次调和的影响可以忽略不计。这些分离表明了一种有趣的可能性，即频率跟随和倍频神经群体可能有助于补充功能，以解决注意增强和信号保真度的冲突需求-倍频群体可能为注意力选择调节大量自上而下的信号，而频率跟随群体可能同时保持相对不失真的感觉质量，而无论观察者的认知状态如何。
Frequency-following and frequency-doubling neurons are ubiquitous in both striate and extrastriate visual areas. However, responses from these two types of neural populations have not been effectively compared in humans because previous EEG studies have not successfully dissociated responses from these populations. We devised a light–dark flicker stimulus that unambiguously distinguished these responses as reflected in the first and second harmonics in the steady-state visual evoked potentials. These harmonics revealed the spatial and functional segregation of frequency-following (the first harmonic) and frequency-doubling (the second harmonic) neural populations. Spatially, the first and second harmonics in steady-state visual evoked potentials exhibited divergent posterior scalp topographies for a broad range of EEG frequencies. The scalp maximum was medial for the first harmonic and contralateral for the second harmonic, a divergence not attributable to absolute response frequency. Functionally, voluntary visual–spatial attention strongly modulated the second harmonic but had negligible effects on the simultaneously elicited first harmonic. These dissociations suggest an intriguing possibility that frequency-following and frequency-doubling neural populations may contribute complementary functions to resolve the conflicting demands of attentional enhancement and signal fidelity—the frequency-doubling population may mediate substantial top–down signal modulation for attentional selection, whereas the frequency-following population may simultaneously preserve relatively undistorted sensory qualities regardless of the observer’s cognitive state.
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影响因子：
1.8
作者：
Di Russo, F;Spinelli, D;Morrone, MC
通讯作者：
Morrone, MC
影响因子：
2.5
作者：
DESIMONE, R;SCHEIN, SJ
通讯作者：
SCHEIN, SJ
DOI：
10.1098/rstb.2000.0560
发表时间：
2000-02-29
影响因子：
6.3
作者：
Friston, KJ
通讯作者：
Friston, KJ
DOI：
10.1080/14640749108400960
发表时间：
1991-11-01
期刊：
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY SECTION A-HUMAN EXPERIMENTAL PSYCHOLOGY
影响因子：
--
作者：
CHEAL, ML;LYON, DR
通讯作者：
LYON, DR
DOI：
10.1037/0096-1523.20.4.887
发表时间：
1994-08-01
影响因子：
2.1
作者：
LUCK, SJ;HILLYARD, SA;HAWKINS, HL
通讯作者：
HAWKINS, HL